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- ...h [[natural selection]] and other [[evolution]]ary processes acts. Without mutation, there are no new [[gene]]s, no new [[allele]]s and, eventually, no evoluti ...], where mutations occur up to 100 times more frequently than the normal [[mutation rate]]. A hotspot can be at an unusual base, e.g., 5-methylcytosine.13 KB (2,019 words) - 00:14, 11 November 2007
- #REDIRECT[[mutation]]21 bytes (2 words) - 20:01, 21 June 2007
- 97 bytes (13 words) - 06:26, 23 May 2008
- 12 bytes (1 word) - 00:14, 11 November 2007
- Auto-populated based on [[Special:WhatLinksHere/Mutation]]. Needs checking by a human.1 KB (167 words) - 18:44, 11 January 2010
Page text matches
- #REDIRECT [[Mutation]]22 bytes (2 words) - 19:42, 21 June 2007
- #REDIRECT[[mutation]]21 bytes (2 words) - 20:02, 21 June 2007
- #REDIRECT[[mutation]]21 bytes (2 words) - 20:01, 21 June 2007
- #REDIRECT[[mutation]]21 bytes (2 words) - 20:05, 21 June 2007
- ...ts; originally thought to be inheritable but possibly due to a spontaneous mutation163 bytes (21 words) - 17:29, 30 July 2010
- An [[X-linked]] [[recessive]] form of [[spinal muscular atrophy]] due to a mutation of the gene encoding the [[androgen receptor]].167 bytes (22 words) - 15:32, 23 February 2010
- ...F, Buser AS, Teo SS, Tiedt R, Passweg JR et al.| title=A gain-of-function mutation of JAK2 in myeloproliferative disorders. | journal=N Engl J Med | year= 2001 KB (190 words) - 20:53, 22 August 2010
- (AIS) Due to a mutation in the androgen receptor such that genetically male individuals (XY) do not321 bytes (52 words) - 13:18, 14 January 2009
- {{r|Mutation}}324 bytes (41 words) - 14:51, 17 March 2010
- {{r|gene mutation}}251 bytes (35 words) - 14:39, 13 December 2008
- {{r|Mutation}}175 bytes (21 words) - 20:29, 11 November 2007
- {{r|Mutation}}237 bytes (27 words) - 01:00, 9 February 2010
- ...of high potassium levels, sodium channels fail to activate properly. The mutation causes single [[amino acid]] changes in parts of the channel which importan2 KB (233 words) - 15:46, 14 February 2009
- ...s with [[DNA]]-damaging mutagens. Neither method is useful for producing a mutation in a specific [[genome|genomic]] location, nor are the techniques applicabl ...ntroduced in the 1980s to surmount these difficulties and allow specific [[mutation]]s to be induced in [[mammal]]ian cells. Even a mammalian [[somatic]] [[cel2 KB (346 words) - 00:44, 8 May 2008
- ...ntricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated prote482 bytes (77 words) - 11:57, 2 July 2009
- {{r|Mutation}}493 bytes (63 words) - 16:51, 11 January 2010
- {{r|Mutation}}478 bytes (61 words) - 17:20, 11 January 2010
- {{r|Mutation}}545 bytes (72 words) - 17:10, 11 January 2010
- {{r|Mutation}}522 bytes (69 words) - 20:49, 11 January 2010
- ...indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are Rom702 bytes (91 words) - 01:33, 11 June 2010
- {{r|Space Quest V: The Next Mutation}}516 bytes (78 words) - 09:06, 7 April 2010
- {{r|Mutation}}836 bytes (104 words) - 06:18, 23 May 2010
- {{r|Mutation}}606 bytes (81 words) - 21:04, 11 January 2010
- {{r|Mutation}}715 bytes (95 words) - 17:20, 11 January 2010
- {{r|Mutation}}643 bytes (89 words) - 05:10, 9 June 2009
- {{r|Mutation}}728 bytes (86 words) - 21:08, 17 April 2011
- {{r|Mutation}}869 bytes (109 words) - 16:26, 11 January 2010
- {{r|Mutation}}791 bytes (103 words) - 07:44, 8 January 2010
- {{r|Mutation}}831 bytes (112 words) - 19:43, 11 January 2010
- {{r|Mutation}}855 bytes (110 words) - 21:04, 11 January 2010
- ...le = Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers886 bytes (120 words) - 11:57, 24 October 2010
- Some used "[[mutation]]" to refer to variations with low allele frequency. ...if a different polypeptide sequence is produced they are ''[[nonsynonymous mutation|nonsynonymous]]''.7 KB (957 words) - 10:47, 30 March 2010
- {{r|Mutation}}1,006 bytes (130 words) - 10:50, 11 January 2010
- ...le = Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers965 bytes (129 words) - 22:06, 22 August 2010
- ...s'' is the inability to respond to vaopressin, (for instance if there is a mutation affecting the V2 vasopressin receptor) and cannot be treated in this way. ...hypothalamic diabetes insipidus is most commonly a consequence of a point mutation in the vasopressin gene, usually in the region coding for vasopressin-assoc4 KB (506 words) - 09:39, 24 July 2011
- ...//www.blackwellpublishing.com/ridley/classictexts/wright.asp "The roles of mutation, inbreeding, crossbreeding and selection in evolution"] ''Proc. 6th Int. Co1 KB (149 words) - 23:10, 15 February 2009
- ...ooks at how large scale changes may be caused by evolutionary mechanisms—[[mutation]], [[migration]], [[genetic drift]], and [[natural selection]].<ref>[http:/1 KB (169 words) - 06:31, 31 May 2009
- Auto-populated based on [[Special:WhatLinksHere/Mutation]]. Needs checking by a human.1 KB (167 words) - 18:44, 11 January 2010
- ...h [[natural selection]] and other [[evolution]]ary processes acts. Without mutation, there are no new [[gene]]s, no new [[allele]]s and, eventually, no evoluti ...], where mutations occur up to 100 times more frequently than the normal [[mutation rate]]. A hotspot can be at an unusual base, e.g., 5-methylcytosine.13 KB (2,019 words) - 00:14, 11 November 2007
- ...indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are Rom ...siology involving the [[voltage-gated potassium channel]]. It results from mutation of KCNQ1 gene (Subtype 1 or JLN1) or the KCNE1 gene (Subtype 2 or JLN2).."<4 KB (593 words) - 10:17, 25 March 2011
- ...man}}</ref> and the formation of 5-HOU is the largest contributor for this mutation, because the base that was formally a cytosine base paired with guanine, is4 KB (593 words) - 13:27, 19 June 2008
- ...] to promote [[natriuresis]], and hence a deficiency of this peptide, or a mutation of the receptor results in salt-sensitive hypertension in mice.1 KB (168 words) - 04:18, 14 May 2023
- ...e quantitative estimates of viral titers, measurement of recombination and mutation rates, the statistical validation of radioactive decay measurements, and th2 KB (255 words) - 23:05, 24 February 2010
- {{r|Mutation}} {{r|Mutation}}5 KB (593 words) - 10:53, 12 May 2023
- ...a pore through which ions flow, carrying type A potassium current (IA). A mutation in the Sh gene reduces the conductance of charge across the neuron since th2 KB (245 words) - 09:23, 14 September 2013
- ...test for some lissencephaly variants, but only those with a known genetic mutation. ...ncy. There are also a number of genetic causes of lissencephaly, including mutation of the [[reelin]] gene (on [[chromosome 7]]),<ref>Hong SE, Shugart YY, Huan7 KB (972 words) - 21:31, 9 July 2011
- Examples include prothrombin gene G-->A20210 mutation.<ref name="pmid9669991">{{cite journal| author=Margaglione M, Brancaccio V, | [[Methylenetetrahydrofolate reductase]] mutation||colspan="2" align="center"|No association4 KB (517 words) - 15:32, 12 November 2010
- {{r|Mutation}}2 KB (265 words) - 10:53, 11 January 2010
- ...I. A punctual mutation was found in nucleotide 1367 of the rpoBgene. That mutation show strains of rifampin-resistant M.leprae in two of the three patients t3 KB (505 words) - 17:04, 18 August 2010
- ...erimental evolution studies, those with rapid [[generation time]]s, high [[mutation rate]]s, large [[population size]]s, and small sizes increase the feasibili ...epistasis, the effect of each mutation declines with increasing numbers of mutation. Understanding whether the majority of genetic interactions are synergistic10 KB (1,507 words) - 02:21, 8 May 2008
- ...l to the parent(s), thus allowing evolution to proceed by means other than mutation.5 KB (751 words) - 03:31, 28 January 2012
- ...e = Neutrophil elastase and granulocyte colony-stimulating factor receptor mutation analyses and leukemia evolution in severe congenital neutropenia patients b ...ient had an ELA-2 defect but her parents did not, suggesting a spontaneous mutation.<ref name=Carlsson/>4 KB (548 words) - 18:07, 30 July 2010
- ...ferred heterodimeric partner (4). On the other hand, overexpression and/or mutation of ErbB-2 are thought to lead to spontaneous dimerisation and the stabiliza2 KB (308 words) - 06:03, 16 July 2010
- ...eptin's role in energy balance came from ''db/db'' mice. These mice have a mutation in the gene coding for leptin receptors and therefore, even though their ad Experiment ii) shows that a single mutation in the ''ob'' gene prevents leptin synthesis, this has also been proven to8 KB (1,203 words) - 20:25, 16 September 2020
- ...etection of DNA can help in "detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relat2 KB (331 words) - 07:01, 17 August 2016
- Mutation in the UDP-glycuronosyltransferase gene cause [[Gilbert Syndrome]]<ref>{{O3 KB (340 words) - 06:00, 12 April 2010
- ..., Torgerson TR, Russell LJ, Lejtenyi C et al.| title=FOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndrome. | journal=N Engl J Med | year=3 KB (360 words) - 17:49, 23 August 2010
- ...is/her offspring, presuming that his/her partner does not also carry the [[mutation]].5 KB (666 words) - 22:24, 1 July 2010
- ...e of vowel mutation more commonly referred to as ''[[i-umlaut]]'' (UK: ''i-mutation''). The [[French language|French]] term ''mouillure'' (German ''Mouillierun6 KB (817 words) - 17:14, 5 June 2008
- * Caporale, LH (2003) Natural selection and emergence of mutation phenotype: An Update of the Evolutionary Synthesis Considering Mechanisms t2 KB (301 words) - 10:28, 12 October 2007
- Caused by mutation, the pathway for Vocal Learning developed out of a pre-existing non-vocal m2 KB (320 words) - 18:33, 4 May 2010
- === Mutation === ...nt, and anticipated, by decades, the subsequent work on [[adaptation]] and mutation by bacterial chemists and microbiologists.9 KB (1,423 words) - 16:37, 23 September 2013
- === Mutation === ...nt, and anticipated, by decades, the subsequent work on [[adaptation]] and mutation by bacterial chemists and microbiologists.9 KB (1,433 words) - 16:34, 23 September 2013
- ...sed. While [[codon]]s for different [[amino acid]]s may change in a random mutation (changing the sequence coding a gene), this doesn't necessarily alter the p3 KB (441 words) - 14:01, 26 September 2007
- | title = The Mutation of the Russian Secret services | url =http://www.agentura.ru/english/dosie/mutation/}}</ref> A small analysis group, on the order of 10 people, had assisted th3 KB (405 words) - 07:39, 21 January 2009
- ...age virtually all types of macromolecules: carbohydrates, nucleic acids ([[mutation]]s), lipids ([[lipid peroxidation]]) and amino acids (e.g. conversion of [[3 KB (416 words) - 14:07, 5 November 2007
- ...utations in a large population and then screen the progeny for the desired mutation. A similar process can be used in both plants and prokaryotes.7 KB (1,045 words) - 06:31, 9 June 2009
- ...an Carp]], with little to recommend it as a potential aquarium fish, but a mutation occurred which developed lovely gold patches on the body which eventually t3 KB (450 words) - 08:53, 2 October 2013
- ...] and a liquid.<ref>Ní Chiosáin (1999).</ref> However, under ''[[consonant mutation]]'' (changing consonants according to some rule), other sequences can occur3 KB (437 words) - 00:44, 26 February 2009
- ...he repetitive nature of these sequences causes the rapid accumulation of [[mutation]]s, which allows their use as highly variable [[molecular markers]]. Such m The high mutation rate of microsatellite loci gives them a far greater resolution than more t10 KB (1,440 words) - 23:48, 12 February 2010
- ...[[cortisol]] is essential for humans, but a few rare individuals with the mutation have shown very similar phenotype to the POMC knockout mouse. <ref>Oswal A, ...a result of a mutation of several genes so it cannot be inferred that PC2 mutation is solely responsible for the obese and hyperphagic phenotype.10 KB (1,388 words) - 10:34, 24 July 2011
- {{r|Mutation}}4 KB (486 words) - 19:46, 11 January 2010
- A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations r ===Mechanisms of Mutation===17 KB (2,672 words) - 11:15, 22 February 2010
- ...ntageous [[mutation]] occurs in an asexual line, it is impossible for that mutation to spread without wiping out all other lines, which may have different adva8 KB (1,190 words) - 07:11, 9 June 2009
- ...n works. Some researchers give credit to [[natural selection]], wherein [[mutation]]s outside of human control make some members of a species more compatible ...m mutation near the beginning of wheat's [[cultivation]]. Wheat with this mutation was the only wheat harvested and became the seed for the next crop. This w18 KB (2,690 words) - 10:14, 26 March 2024
- ...Adolf Eduard Driesch]], and [[Hugo Marie de Vries]] (the gene concept, and mutation theory) all working in the period spanning the mid to late 19th through the4 KB (621 words) - 16:36, 7 June 2009
- .../wales/learnwelsh/bigwelshchallenge/south/notes/nasal_mutation.shtml Nasal mutation]'.</ref> Even place-names undergo softening of the initial consonant: for e5 KB (675 words) - 11:11, 24 January 2011
- ...aternal in origin. The more of these loci that are deleted or affected by mutation, the more severe will be the manifestations of the disease: ...toxic aggregates. The severity of the damage depends on the nature of the mutation. Some mutations (β<sup>o</sup>) prevent any formation of β chains; others23 KB (3,285 words) - 17:32, 11 March 2024
- *You, L., and J. Yin. 2002. Dependence of epistasis on environment and mutation severity as revealed by in silico mutagenesis of phage T7. Genetics. 160:12 *Poon, A., and L. Chao. 2005. The rate of compensatory mutation in the DNA bacteriophage _X174. Genetics. 170:989-999.12 KB (1,795 words) - 02:11, 8 May 2008
- ..., the mutations are likely to be identical by descent rather than multiple mutation events occurring at the same site.”10 KB (1,623 words) - 21:25, 1 November 2009
- ...] and a liquid.<ref>Ní Chiosáin (1999).</ref> However, under ''[[consonant mutation]]'' (changing consonants according to some rule), other sequences can occur4 KB (656 words) - 09:43, 30 December 2011
- ...ne product, which in turn affects pigmentation.<ref name=OCA2/> A specific mutation within the ''HERC2'' gene, a gene that regulates ''OCA2'' expression, is pa ...Roger | last=Highfield | date=2008-01-30}}</ref> Eiberg stated, "A genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a 's26 KB (4,056 words) - 18:41, 3 March 2024
- ...AG in the 23S r RNA. This gene codes for a ribosomal subunit of 50S. The mutation occurred at the point A2058G. The mutated ribosome is not able to bind to t11 KB (1,712 words) - 22:05, 7 February 2010
- 3. Clément K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.4 KB (538 words) - 07:40, 12 October 2010
- ...ase activation. Only one family have been found to have a leptin receptor mutation which were homozygotes were hyperphagic, obese, growth retarded and had hyp ...e normal physiology of POMC and melanocortins, that the phenotype for POMC mutation would show obesity, pigmentation changes and ACTH deficiency. Two patients21 KB (3,145 words) - 15:26, 25 February 2023
- ...ozygous]]) makes a person a carrier who can pass this mutation onward. One mutation may lead to slightly excessive iron absorption but usually haemochromatosis ...e [[Human_leukocyte_antigen|HLA-A3]] [[locus]]. Homozygosity for the C282Y mutation is the most significant, although hemochromatosis for the heterozygosity fo24 KB (3,263 words) - 14:11, 25 June 2010
- Transposons may lose their ability to synthesize transposase through mutation, yet continue to jump through the genome because other transposons are stil Transposons can cause [[mutation]]. They do this either by being inserted into the coding region of a gene,22 KB (3,191 words) - 07:32, 31 December 2007
- ...2_-O positions with the use of methytransferase (MTase). If there is a mutation found in both of these methylation points, it is lethal to the virus. The d ...of virulence in a mouse model.” <ref name=griven/> However, other cases of mutation and formation of different strains can be explained by genetic drift and na15 KB (2,311 words) - 20:25, 18 January 2010
- ==== Single nucleotide polymorphism (SNP): [[mutation]] in one base ====17 KB (2,525 words) - 03:39, 20 July 2013
- :*Are there particular conditions that select for novelty and for high mutation or recombination rates? What about for cooperative behavior?7 KB (981 words) - 13:26, 22 August 2013
- ...t show the similar degree of reduced variation predicted for below-average mutation rates. Since neither selection nor low mutation frequency can explain the similar DNA between the grasses, the authors conc19 KB (2,833 words) - 22:11, 14 February 2010
- ...ng populations as a result of the interaction of [[natural selection]], [[mutation]], migration and genetic drift. The work of Fisher, Wright, and Haldane on7 KB (990 words) - 08:51, 30 June 2023
- ...y known. These include all the mechanisms of inheritance, the phenomena of mutation, of migration, of the effect of limited population size, and of the operati === Mutation rates in humans===22 KB (3,306 words) - 21:10, 17 April 2014
- ...cation of the original DNA sequence. The transposition process can cause [[mutation]]s at the site of DNA insertion, and can cause increases in the total amoun ...e their ability to synthesize reverse transcriptase or transposase through mutation, yet continue to jump through the genome because other transposons are stil18 KB (2,605 words) - 07:29, 9 June 2009
- ...ismarck tradition to the liberal type? The German welfare state: change or mutation ?7 KB (945 words) - 18:22, 9 October 2020
- ...mutations per gene per generation. Some bacteria can increase the rate of mutation during DNA replication as a response to stress. ...frequent genetic changes in bacterial genomes come from [[mutation|random mutation]]. Bacteria can also undergo genetic recombination. Many bacteria can take-26 KB (3,840 words) - 09:16, 6 March 2024
- ...programmed aging-resistance) and theories that link aging with DNA damage/mutation or [[DNA repair]] capability. ...e span 110%<ref>{{cite journal | author=Friedman DB, Johnson TE. | title=A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces herm19 KB (2,674 words) - 03:05, 17 February 2010
- ...as Hunt Morgan]] proposed a theory of sex-linked inheritance for the first mutation discovered in the fruit fly, [[Drosophila]], white eye.8 KB (1,066 words) - 11:36, 15 September 2013
- ...[[X-ray]]s as a [[mutagen]]. (Exposure to X-rays can increase the rate of mutation above the natural background level, making it a powerful research tool for ...ond, it demonstrated a source of large-scale mutation. As a cause of major mutation, it remains an area of interest in [[cancer]] research today.27 KB (4,053 words) - 12:30, 6 September 2013
- ...[[X-ray]]s as a [[mutagen]]. (Exposure to X-rays can increase the rate of mutation above the natural background level, making it a powerful research tool for ...ond, it demonstrated a source of large-scale mutation. As a cause of major mutation, it remains an area of interest in [[cancer]] research today.27 KB (4,047 words) - 04:39, 26 October 2013