Protein kinase/Related Articles
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- Adenosine triphosphate : A molecule sometimes called the "energy currency" of a cell
- Antineoplastic agent : Drug that prevents the development, maturation, or spread of neoplastic cells.
- Cyclic AMP : An adenine nucleotide that is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
- Cyclic GMP : A guanine nucleotide that is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases.
- Drug discovery : Process by which pharmaceuticals are discovered and/or designed.
- G-protein-coupled receptor kinase : A family of protein kinases which regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating their intracellular domains after their associated G proteins have been released and activated.
- G-protein-coupled receptor : Protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses.
- Phospholipase : Enzyme of four major classes, that hydrolyzes phospholipids into fatty acids and other lipophilic substances.
- Protein : A polymer of amino acids; basic building block of living systems.
- Second messenger system : Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter.
- Signal transduction : The intercellular or intracellular transfer of information (biological activation/inhibition) through a signal pathway.