In medicine, tension headache, also called tension-type headache, stress headache or idiopathic headache, is a "common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) pain of mild to moderate intensity in the head; scalp; or neck. the subtypes are classified by frequency and severity of symptoms. there is no clear cause even though it has been associated with muscle contraction and stress.
Tricyclic antidepressants may be effective and may be more effective than second-generation antidepressants acccording to a systematic review. Another systematic review concluded that it is not clear whether any medications taken daily can prevent tension headaches. However, several randomized controlled trials of antidepressant agents included in the systematic review were positive.
|Ashina||"The lower platelet 5-HT during treatment with citalopram than amitriptyline indicates that 5-HT reuptake was most effectively inhibited by citalopram. In contrast, amitriptyline was most effective in reduction of headache."|
|Göbel||"In the amitriptyline group, a significant reduction in daily headache duration was already found in the 3rd week of treatment."|
|Holroyd||"Cognitive-behavioral therapy and amitriptyline each yielded clinically significant improvements in headache activity...Neither treatment, however, eliminated headache problems.." (no placebo group)|
|Holroyd||"Our results indicate that antidepressant medication and stress management therapy are each modestly effective in treating chronic tension-type headaches. "|
|Pfaffenrath||"Treatment response occurred in 30.3% of the amitriptylinoxide, 22.4% of the amitriptyline and 21.9% of the placebo group."|
- Anonymous (2020), Tension headache (English). Medical Subject Headings. U.S. National Library of Medicine.
- International Headache Society. IHS Classification ICHD-II Tension-type headache
- Ad Hoc Committee on the Classification of Headache of the National Institute of Neurological Diseases and Blindness. Classification of headache. JAMA (1962) 179:717–8
- Jackson JL, Shimeall W, Sessums L, Dezee KJ, Becher D, Diemer M et al. (2010). "Tricyclic antidepressants and headaches: systematic review and meta-analysis.". BMJ 341: c5222. DOI:10.1136/bmj.c5222. PMID 20961988. PMC PMC2958257. Research Blogging.
- Verhagen AP, Damen L, Berger MY, Passchier J, Koes BW (2010). "Lack of benefit for prophylactic drugs of tension-type headache in adults: a systematic review.". Fam Pract 27 (2): 151-65. DOI:10.1093/fampra/cmp089. PMID 20028727. Research Blogging.
- Ashina S, Bendtsen L, Jensen R (2004). "Analgesic effect of amitriptyline in chronic tension-type headache is not directly related to serotonin reuptake inhibition.". Pain 108 (1-2): 108-14. DOI:10.1016/j.pain.2003.12.012. PMID 15109513. Research Blogging.
- Bendtsen L, Jensen R (2000). "Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache.". Cephalalgia 20 (6): 603-10. PMID 11075846.
- Göbel H, Hamouz V, Hansen C, Heininger K, Hirsch S, Lindner V et al. (1994). "Chronic tension-type headache: amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings.". Pain 59 (2): 241-9. PMID 7892022.
- Holroyd KA, Nash JM, Pingel JD, Cordingley GE, Jerome A (1991). "A comparison of pharmacological (amitriptyline HCL) and nonpharmacological (cognitive-behavioral) therapies for chronic tension headaches.". J Consult Clin Psychol 59 (3): 387-93. PMID 2071723.
- Holroyd KA, O'Donnell FJ, Stensland M, Lipchik GL, Cordingley GE, Carlson BW (2001). "Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial.". JAMA 285 (17): 2208-15. PMID 11325322. PMC PMC2128735.
- Pfaffenrath et al. Efficacy and Tolerability of Amitriptylinoxide in the Treatment of Chronic Tension-Type Headache: A Multi-Centre Controlled Study Cephalalgia April 1994 14: 149-155, DOI:10.1046/j.1468-2982.1994.1402149.x
- Jackson JL, Kuriyama A, Hayashino Y (2012). "Botulinum toxin A for prophylactic treatment of migraine and tension headaches in adults: a meta-analysis.". JAMA 307 (16): 1736-45. DOI:10.1001/jama.2012.505. PMID 22535858. Research Blogging.