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Citalopram

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In psychiatry, citalopram is a second-generation antidepressant for treating major depressive disorder.

History

Efficacy

Pharmacology

Administration

Distribution

Metabolism

Citalopram is metabolised by cytochrome P-450 CYP3A4 and CYP2C19.

Excretion

Toxicity

Drug toxicity includes arrhythmias. The United States Food and Drug Administration has issued a warning to not use higher doses because of use of the cytochrome P-450 system and also arrhythmias.[1]

External links

The most up-to-date information about Citalopram and other drugs can be found at the following sites.


References

  1. anonymous (2012 [last update]). Safety Alerts for Human Medical Products > Celexa (citalopram hydrobromide) - Drug Safety Communication: Revised Recommendations, Potential Risk of Abnormal Heart Rhythms. fda.gov. Retrieved on March 29, 2012.