From Citizendium
Jump to navigation Jump to search
This article is developing and not approved.
Main Article
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
Video [?]
A list of key readings about Neuroimaging.
Please sort and annotate in a user-friendly manner. For formatting, consider using automated reference wikification.

This list should eventually be split into sections - e.g. structural vs. functional imaging, clinical vs. psychological vs. comparative, or developmental vs. learning vs. aging vs. diagnostic vs. comparative. Some of these references may fit better onto the bibliographies of some of the related pages.

Describes a measurement of magnetic field gradients and magnetic forces, based on FLASH-MRI data obtained at 4 T from 118 healthy human subjects (of which 100 males) aged between 18 and 60 years. Concludes that "the induced magnetic force is highly significant in the eyeballs, orbitofrontal and temporal cortices, subcallosal gyrus, anterior cingulate as well as midbrain and brainstem (pons), regardless of subjects' age or gender. "
Provides an overview on the state of the art in functional Magnetic Resonance Imaging as of mid-2009, focusing on the following seven interrelated topics:
"(1) Clinical impact, (2) Utilization of individual functional maps, (3) fMRI signal interpretation, (4) Pattern effect mapping and decoding, (5) Endogenous oscillations, (6) MRI technology, and (7) Alternative functional contrast mechanisms."
Synchrotron-based neuroimaging of what may be the oldest known fossil brain.
Suggests a framework for the study of the brain in model organisms at a mesoscopic scale, i.e. at length scales between the microscopic (≤ 100μm) and macroscopic (≥ several mm) levels. Based on the experience with the impact of wide-spread data sharing in other scientific disciplines (e.g. genomics), the criteria for a centralized knowledge repository on mesoscopic aspects of the brain in the rat, the macaque and humans are laid out.
  • Steinbeis, N.; Koelsch, S. (2008). "Comparing the Processing of Music and Language Meaning Using EEG and fMRI Provides Evidence for Similar and Distinct Neural Representations". PLoS ONE 3 (5). DOI:10.1371/journal.pone.0002226. Research Blogging.
A brief and balanced overview over the genetic mechanisms currently deemed relevant for the evolution of the human brain, along with pointers to some related methodological issues.
Quote relevant to neuroimaging:

"...comparative genomics, which has been the main workhorse of current studies, needs to be complemented by cleverly designed in vivo and in vitro functional experiments aimed at probing the exact phenotypic consequence of evolutionary changes in DNA sequence."

Quote relevant to neuroimaging:

"We anticipate that clinical use of neuroimaging modalities in psychiatry will increase dramatically in the near future and suggest that clinicians need to be aware of the potential applications."

A well-written overview over the history of neuroimaging.
Briefly reviews the state of the art of high resolution magnetic resonance imaging in the living brain and answers the question in the title basically positively. Quote from the conclusions: "While being able to understand the relationship between brain structure and function is likely to be crucial in attaining a complete understanding of the brain, the potential of this in vivo technique for understanding diseases of the brain is considerable. It is currently very difficult to detect many neurodegenerative diseases such as Alzheimer's and Parkinson's until there has been considerable damage to the brain and patients have begun to show symptoms. If these diseases could be detected at an earlier stage, the opportunities for pre-symptomatic treatment are much greater. In the future, high resolution magnetic resonance imaging could become a standard method of detecting pathological changes in the brain at the earliest possible occasion, leading to treatment and the minimization of irreversible damage."
  • Mechelli, A.; Price, C.J.; Friston, K.J.; Ashburner, J. (2005). "Voxel-Based Morphometry of the Human Brain: Methods and Applications". Current Medical Imaging Reviews 1 (2): 105-113. DOI:10.2174/1573405054038726. Research Blogging.