The N-methyl-d-aspartate receptor (NMDA receptor) is the binding site for glutamate, n-methyl-d-aspartate and glycine. NMDA receptors are ionotropic as they allow calcium and sodium ions to flow into the cell while potassium ions leave. This excitatory change hypopolarizes the cell and makes it more likely to fire.
NMDA receptors are implicated in memory and learning through the process of long-term potentiation.
NMDA receptor inhibitors
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