Diabetes mellitus type 1

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Diabetes mellitus type 1 is a "subtype of diabetes mellitus that is characterized by insulin deficiency. It is manifested by the sudden onset of severe hyperglycemia, rapid progression to diabetic ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence."[1]

Etiology

Autoantibodies to glutamate decarboxylase is associated with diabetes mellitus type 1.[2][3][4]

Complications

Diabetic foot

For more information, see: Diabetic foot.


Neuropathy

For more information, see: Diabetic neuropathy.

Nephropathy

References

  1. Anonymous (2023), Diabetes Mellitus, Type I (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. GLUTAMATE DECARBOXYLASE 1; GAD1. (Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 605363. World Wide Web URL: http://omim.org/.)
  3. GLUTAMATE DECARBOXYLASE 2; GAD2. (Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 138275. World Wide Web URL: http://omim.org/.)
  4. GLUTAMATE DECARBOXYLASE 3; GAD3. (Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 138276. World Wide Web URL: http://omim.org/.)