In endocrinology, autoimmune polyendocrinopathies, also called polyglandular autoimmune syndrome or autoimmune polyendocrine syndrome (APS), are "autoimmune diseases affecting multiple endocrine organs.
- "Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (candidiasis, chronic mucocutaneous)."
- "Type II exhibits any combination of adrenal insufficiency (addison's disease), lymphocytic thyroiditis (thyroiditis, autoimmune;), hypoparathyroidism; and gonadal failure." Type II is also called Schmidt's Syndrome if Addison disease is present.
"In both types organ-specific antibodies against a variety of endocrine glands have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present."
- Anonymous (2021), Autoimmune polyendocrinopathy (English). Medical Subject Headings. U.S. National Library of Medicine.
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