From Citizendium, the Citizens' Compendium
- See also changes related to Lovastatin, or pages that link to Lovastatin or to this page or whose text .
- Hydroxymethylglutaryl-coenzyme A reductase inhibitor : HMG-CoA reductase inhibitors which reduce 3-hydroxy-3-methyl-glutaryl CoA and lower cholesterol synthesis.
- Hypercholesterolemia : Presence of an abnormally large amount of cholesterol in the cells and plasma of the circulating blood.
- Cholesterol : Principal sterol of all higher animals.
Type I statins
- Mevalonate : A key chemical precursor in the biosynthesis of cholesterol.
- Lovastatin : Type I statin and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor used to treat hypercholesterolemia.
- Pravastatin : Type I Statin used to treat hypercholesterolemia.
- Simvastatin : A semisynthetic lipid-lowering drug derived from a compound produced by a mold of the genus Aspergillus and administered orally to lower a high cholesterol level in the blood by inhibiting the action of an enzyme catalyzing the synthesis of cholesterol.
Type II statins
- Fluvastatin : Fluorophenyl-based statin, HMG-CoA reductase inhibitor, for reduction of cholesterol, triglycerides and apo B.
- Cerivastatin : A type II statin formerly used to treat high cholesterol levels (hypercholesterolemia).
- Atorvastatin : Sold as Lipitor®, a type II statin used to treat high cholesterol (hypercholesterolemia),
- Rosuvastatin : A type II statin, marketed as Crestor®, used to treat high cholesterol levels.