Hydroxymethylglutaryl-coenzyme A reductase inhibitor/Related Articles
From Citizendium, the Citizens' Compendium
- See also changes related to Hydroxymethylglutaryl-coenzyme A reductase inhibitor, or pages that link to Hydroxymethylglutaryl-coenzyme A reductase inhibitor or to this page or whose text .
Type 1 statins, based on decalin ring structures
- Mevastatin : Statin drug used to treat hypercholesterolemia by inhibiting the enzyme HMG-CoA reductase.
- Lovastatin : Type I statin and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor used to treat hypercholesterolemia.
- Pravastatin : Type I Statin used to treat hypercholesterolemia.
- Simvastatin : A semisynthetic lipid-lowering drug derived from a compound produced by a mold of the genus Aspergillus and administered orally to lower a high cholesterol level in the blood by inhibiting the action of an enzyme catalyzing the synthesis of cholesterol.
Type 2 statins, based on fluorophenyl ring structures
- Fluvastatin : Fluorophenyl-based statin, HMG-CoA reductase inhibitor, for reduction of cholesterol, triglycerides and apo B.
- Cerivastatin : A type II statin formerly used to treat high cholesterol levels (hypercholesterolemia).
- Atorvastatin : Sold as Lipitor®, a type II statin used to treat high cholesterol (hypercholesterolemia),
- Rosuvastatin : A type II statin, marketed as Crestor®, used to treat high cholesterol levels.