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From Citizendium, the Citizens' Compendium
In medicine and biochemistry, apolipoproteins are "protein components on the surface of lipoproteins. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and lipid metabolism. These proteins are synthesized mainly in the liver and the intestines."
- Apolipoprotein A (apo A) is the structural protein of high density lipoproteins (alpha-lipoproteins).
- Apolipoprotein A-I (apo AI)
- Apolipoprotein A-II
- Apolipoproteins B
- Apolipoproteins C
- Apolipoprotein C-I
- Apolipoprotein C-II
- Apolipoprotein C-III
- Apolipoproteins D
- Apolipoproteins E.
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
Role in dyslipidemias
Hyperlipoproteinemia Type I
Hyperlipoproteinemia Type III
Role as a diagnostic tests
Measurement of blood apolipoproteins and the ratio of apolipoprotein B / apolipoprotein A-I are alternatives to measuring cholesterol levels and the ratio of non–HDL cholesterol / HDL cholesterol in determining risk of vascular disease from atherosclerosis.
- ↑ Anonymous (2014), Apolipoprotein (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Emerging Risk Factors Collaboration. Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK et al. (2009). "Major lipids, apolipoproteins, and risk of vascular disease.". JAMA 302 (18): 1993-2000. DOI:10.1001/jama.2009.1619. PMID 19903920. Research Blogging.