See something needing your input? Click here to Join us in providing quality, expert-guided information to the public for free!
Monthly Honor Roll of Users Editing the Wiki
From Citizendium, the Citizens' Compendium
In medicine and biochemistry, apolipoproteins are "protein components on the surface of lipoproteins. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and lipid metabolism. These proteins are synthesized mainly in the liver and the intestines."
- Apolipoprotein A (apo A) is the structural protein of high density lipoproteins (alpha-lipoproteins).
- Apolipoprotein A-I (apo AI)
- Apolipoprotein A-II
- Apolipoproteins B
- Apolipoproteins C
- Apolipoprotein C-I
- Apolipoprotein C-II
- Apolipoprotein C-III
- Apolipoproteins D
- Apolipoproteins E.
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
Role in dyslipidemias
Hyperlipoproteinemia Type I
Hyperlipoproteinemia Type III
Role as a diagnostic tests
Measurement of blood apolipoproteins and the ratio of apolipoprotein B / apolipoprotein A-I are alternatives to measuring cholesterol levels and the ratio of non–HDL cholesterol / HDL cholesterol in determining risk of vascular disease from atherosclerosis.
- ↑ Anonymous (2013), Apolipoprotein (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Emerging Risk Factors Collaboration. Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK et al. (2009). "Major lipids, apolipoproteins, and risk of vascular disease.". JAMA 302 (18): 1993-2000. DOI:10.1001/jama.2009.1619. PMID 19903920. Research Blogging.