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Podophyllin is a caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains podophyllotoxin and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses."[1]

Podophyllotoxin is the base for a class of antineoplastic agents.
  1. Anonymous (2020), Podophyllin (English). Medical Subject Headings. U.S. National Library of Medicine.