Aminostatic hypothesis/Bibliography

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A list of key readings about Aminostatic hypothesis.
Please sort and annotate in a user-friendly manner. For formatting, consider using automated reference wikification.

(1) Anderson G.H., Edmund T.S., Li S.P., Anthony L.T.N, Bialik R. (1994) Dissociation between plasma and brain amino acid profiles and short-term food intake in the rat. Am J Physiol 266:1675-86.

(2) Brehm B.J., D'Alessio D.A. (2008) Benefits of high-protein weight loss diets: enough evidence for practice? Curr Opin Endocrinol Diabetes Obes 15: 416-421.

  • cant access but have emailed Gareth for help

(3) Halton T.L., Hu F.B. (2004) The Effects of High Protein Diets on Thermogenesis, Satiety and Weight Loss: A Critical Review. J Am Coll Nutr 23:373-385.

Many popular diets today advocate that increased ingestion of high-protein foods facilitates weight loss. This paper examines the effects of high protein diets on energy expenditure, energy intake and weight loss . Evidence that high protein diets affect thermogenesis and satiety are discussed. Gianna Maurer 14:34, 16 October 2011 (UTC)

(4) Harper A.E., Peters J.C. (1989) Protein intake, brain amino acid and serotonin concentrations and protein self-selection. J Nutr 119:677-689.

(5) Lejeune M.P., Westerterp K.R., Adam T.C., Luscombe-Marsh N.D., Westerterp-Plantenga M.S. (2006) Ghrelin and glucagon-like peptide 1 concentrations, 24-h satiety, and energy and substrate metabolism during a high-protein diet and measured in a respiration chamber. Am J Clin Nutr 83:89-94.

(6) Mellinkoff S.M., Frankland M., Boyle D., Greipel M. (1956) Relationship between serum amino acid concentration and fluctuations in appetite. J Appl Physiol 8:535-538.

First paper suggesting a role for amino acid metabolism in the regulation of hunger – the aminostatic hypothesis. A reciprocal relationship between serum amino acid concentration and appetite is proposed. Gianna Maurer 14:04, 16 October 2011 (UTC)

(7) Potier M., Darcel N., Tome D. (2009) Protein, amino acids and the control of food intake. Curr Opin Clin Nutr Metab Care 12:54-58.

  • cant access journal!!

(8) Tome D. (2004) Protein, amino acids and the control of food intake. Br J Nutr 92:27-30.

A comprehensive review discussing the influence of protein and amino acids on appetite and the control of food intake. The paper explains theories behind the aminostatic hypothesis as well as evaluates proposed signalling pathways involved in amino acid monitoring. Gianna Maurer 14:18, 16 October 2011 (UTC)

(9) Tome D., Schwarz J., Darcel N., Fromentin G. (2009) Protein, amino acids, vagus nerve signaling, and the brain. Am J Clin Nutr 90:838-843.

“Complex pathways are involved in protein and amino acid signalling to the brain. The signals to the brain associated with the ingestion of amino acids […] originate from the visceral and metabolic processes and involve both indirect (mainly vagus mediated) and direct (plasma concentrations of nutrients and hormones) pathways. Gut hormones (cholecystokinin, GLP-1, and PYY) presently are major signalling candidates, acting either indirectly by activation of the vagus pathway (cholecystokinin, GLP-1) or directly at the level of the hypothalamus (PYY).” Gianna Maurer 14:47, 16 October 2011 (UTC)

(10) Westerterp-Plantenga M.S. (2008) Protein intake and energy balance. Regul Pept 149:67-69.

"Elevated protein intake plays a key role [in maintaining energy balance in the context of body-weight regulation], through (i) increased satiety related to increased diet-induced thermogenesis, (ii) its effect on thermogenesis, (iii) body composition, and (iv) decreased energy-efficiency" Gianna Maurer 15:06, 16 October 2011 (UTC)

(11) Zeng Y., Li S., Xiong G., Su H., Wan J. (Influences of protein to energy ratios in breakfast on mood, alertness and attention in the healthy undergraduate students

(12) Hochstenbach-Waelen, A. Veldhorst, M.A.B. Nieuwenhuizen, A.G. Westerterp-Plantenga, M.S. Westerterp, K.R., (2009)Comparison of 2 diets with either 25% or 10% of energy as casein on energy expenditure, substrate balance, and appetite profile. Am J Clin Nutr;89:831–8.