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Revision as of 11:31, 1 September 2008 by imported>David E. Volk (New Draft of the Week - made date exception due to long delay)
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Article of the Week [ about ]

Three-dimensional model of the structure of part of a DNA double helix.

Deoxyribonucleic acid (DNA) is a very large biological molecule that is vital in providing information for the development and reproduction of living things. Every living organism has its own DNA sequence that is like a unique 'barcode' or 'fingerprint'. This inheritable variation in DNA is the most important factor driving evolutionary change over many generations. But, beyond these general characteristics, what "exactly" is DNA? What are the precise physical attributes of this molecule that make its role so centrally imposing in understanding life?

DNA is a long polymer of simple units called nucleotides, held together by a sugar phosphate backbone. Attached to each sugar molecule is a molecule of one of four bases; adenine (A), thymine (T), guanine (G) or cytosine (C), and the order of these bases on the DNA strand encodes information. In most organisms, DNA is a double-helix (or duplex molecule) consisting of two DNA strands coiled around each other, and held together by hydrogen bonds between bases. Because of the chemical nature of these bases, adenine always pairs with thymine and guanine always pairs with cytosine. This complementarity forms the basis of semi-conservative DNA replication — it makes it possible for DNA to be copied relatively simply, while accurately preserving its information content. [more...]


New Draft of the Week [ about ]

Although bound up with the tradition of the ‘special library’, information management differs from such earlier concepts in its focus on all kinds of information and a concern for the relationship between information provision and organizational performance. In many special libraries there had long been responsibility for managing internal documentation of various kinds, especially research reports. The history of this development is usefully explored by Black, Muddiman and Plant [1] who note the emergence of information management concepts following the end of the First World War, with the formal organization of ‘information bureaux’ in the establishment of ASLIB (the Association of Special Libraries and Information Bureaux) in the UK in 1924. Some techniques, however, were even older, witness Kaiser’s work on indexing [2][3]. Indeed, we can date many of the ideas of what is now called ‘information management’ (although ‘documentation’ is used as a near equivalent in much of Europe) to the founding by Otlet and La Fontaine of the International Institute of Bibliography in 1895 [more...]