Zanamivir

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Zanamivir structure.jpg
zanamivir
IUPAC name: see chemistry section
Synonyms: Relenza®
Formula: C12H20N4O7

 Uses: influenza A & B

 Properties: neuraminidase inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
332.3098 139110-80-8


Zanamivir is a guanido-neuraminic acid that is a neuraminidase inhibitor used as an antiviral drug to treat influenza A and B.

Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C12H20N4O7.

Dosage

According to MedMaster, "the recommended dose of RELENZA for treatment of influenza in adults and pediatric patients ages 7 years of age and older is 10 mg twice daily (approximately 12 hours apart) for 5 days." Zanamivir is administered by inhalation and is supplied at 5 mg blister per dose so 20 blisters are needed. One Relenza Diskhaler contains 20 blisters.

Brand names

  • GANA
  • GNA
  • Relenza (GlaxoSmithKline)
  • ZMR
  • Zanamavir

External links

The most up-to-date information about Zanamivir and other drugs can be found at the following sites.