Pulmonary hypertension

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In medicine, pulmonary hypertension is "increased vascular resistance in the pulmonary circulation, usually secondary to heart diseases or lung diseases."[1]

Diagnosis

The echocardiogram may be more than 10 mm/Hg in error in half of cases.[2][3]

A meta-analysis of Doppler echocardiography for predicting right heart catheterization reported a sensitivity and specificity of 88% and 56%, respectively. [4]

Treatment

For all patients, consider:

For patients with New York Heart Association (NYHA) class IV symptoms inspite of calcium-channel antagonists, consider:

Perioperative care

The preoperative care and perioperative care (including intraoperative care and postoperative care) has been reviewed.[5]

Pulmonary hypertensive crisis, also called acute right heart syndrome, may happen when the pulmonary artery pressure is over a mean of 40 mm Hg. If the systemic blood pressure falls below the pulmonary artery pressure, perfusion of the right ventricle may be reduced leading to myocardial ischemia and dilitation of the right ventricle which may lead to systemic hypotension and acidosis.[5]

If the preoperative pulmonary artery systolic pressure is over 70 mm Hg, the risk of postoperative heart failure and mortality may be 10%.[6] Risk factors for operative mortality include:

References

  1. Anonymous (2015), Pulmonary hypertension (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Fisher MR, Forfia PR, Chamera E, et al (April 2009). "Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension". Am. J. Respir. Crit. Care Med. 179 (7): 615–21. DOI:10.1164/rccm.200811-1691OC. PMID 19164700. Research Blogging.
  3. Rich JD, Shah SJ, Swamy RS, Kamp A, Rich S (2011). "Inaccuracy of Doppler echocardiographic estimates of pulmonary artery pressures in patients with pulmonary hypertension: implications for clinical practice.". Chest 139 (5): 988-93. DOI:10.1378/chest.10-1269. PMID 20864617. Research Blogging.
  4. Taleb M, Khuder S, Tinkel J, Khouri SJ (2013). "The diagnostic accuracy of Doppler echocardiography in assessment of pulmonary artery systolic pressure: a meta-analysis.". Echocardiography 30 (3): 258-65. DOI:10.1111/echo.12061. PMID 23227919. Research Blogging.
  5. 5.0 5.1 Hill NS, Roberts KR, Preston IR (2009). "Postoperative pulmonary hypertension: etiology and treatment of a dangerous complication.". Respir Care 54 (7): 958-68. PMID 19558745.
  6. Lai HC, Lai HC, Wang KY, Lee WL, Ting CT, Liu TJ (2007). "Severe pulmonary hypertension complicates postoperative outcome of non-cardiac surgery.". Br J Anaesth 99 (2): 184-90. DOI:10.1093/bja/aem126. PMID 17576968. Research Blogging.