Protein kinase

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In biochemistry, protein kinases are "a family of enzymes that catalyze the conversion of ATP and a protein to ADP and a phosphoprotein."[1]

In signal transduction, cell surface receptors may activate second messenger systems such as adenyl cyclase-cyclic AMP and cyclic GMP which then may activate protein kinases which then affect downstream targets (see figure).[2]

Examples of protein kinases include G-protein-coupled receptor kinases.

References

  1. Anonymous (2015), Protein kinase (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Lodish, Harvey F. (1999). “20.1. Overview of Extracellular Signaling”, Molecular cell biology. New York: Scientific American Books. ISBN 0-7167-3136-3.