Cinoxacin (Cinobac®) is an antibiotic drug use to treat urinary tract infections caused by many aerobic, Gram-negative bacteria. It is active against susceptible strains of E. coli, Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, and Enterobacter species.
Mechanism of action
Cinoxacin's IUPAC chemical name is 1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid and its chemical formula is C12H10N2O5 (MW=262.2182 g/mol). It is related to oxolinic acid and nalidixic acid and it is active over the entire urinary pH range.
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