Thyroid nodule: Difference between revisions
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In medicine, a '''thyroid nodule''' is a "small circumscribed mass in the [[thyroid gland]] that can be of neoplastic growth or non-neoplastic abnormality. | In medicine, a '''thyroid nodule''' is a "small circumscribed mass in the [[thyroid gland]] that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (goiter, nodular)."<ref>{{MeSH}}</ref> About 5% of thyroid nodules, including [[incidentaloma]]s, contain [[thyroid cancer]].<ref name="pmid15496625">{{cite journal |author=Hegedüs L |title=Clinical practice. The thyroid nodule |journal=N. Engl. J. Med. |volume=351 |issue=17 |pages=1764–71 |year=2004 |month=October |pmid=15496625 |doi=10.1056/NEJMcp031436 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=15496625&promo=ONFLNS19 |issn=}}</ref> | ||
A [[decision analysis]] of conflicting [[clinical practice guideline]]s concluded that selected [[biopsy]] of nodules 10-14 mm in size is better than routine biopsies.<ref name="pmid18505762">{{cite journal |author=McCartney CR, Stukenborg GJ |title=Decision analysis of discordant thyroid nodule biopsy guideline criteria |journal=J. Clin. Endocrinol. Metab. |volume=93 |issue=8 |pages=3037–44 |year=2008 |month=August |pmid=18505762 |doi=10.1210/jc.2008-0448 |url=http://jcem.endojournals.org/cgi/pmidlookup?view=long&pmid=18505762 |issn=}}</ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Latest revision as of 18:16, 18 March 2009
In medicine, a thyroid nodule is a "small circumscribed mass in the thyroid gland that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (goiter, nodular)."[1] About 5% of thyroid nodules, including incidentalomas, contain thyroid cancer.[2]
A decision analysis of conflicting clinical practice guidelines concluded that selected biopsy of nodules 10-14 mm in size is better than routine biopsies.[3]
References
- ↑ Anonymous (2024), Thyroid nodule (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Hegedüs L (October 2004). "Clinical practice. The thyroid nodule". N. Engl. J. Med. 351 (17): 1764–71. DOI:10.1056/NEJMcp031436. PMID 15496625. Research Blogging.
- ↑ McCartney CR, Stukenborg GJ (August 2008). "Decision analysis of discordant thyroid nodule biopsy guideline criteria". J. Clin. Endocrinol. Metab. 93 (8): 3037–44. DOI:10.1210/jc.2008-0448. PMID 18505762. Research Blogging.