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...lest class of steroids, the estrogens, are biosynthesized, by the enzyme [[aromatase]], from the androgens by loss of the C-19 <math>\beta</math>-methyl group,

...cated in breast and [[endometrial cancer]]s. Estrogen is produced by the [[aromatase]] enzyme which is present in many tissues including adipose tissue. The pro

...drostenedione]] and [[testosterone]] (which can be directly converted by [[aromatase]] to the estrogens [[estrone]] and [[estradiol]], respectively). Increased ...lized, with possible adjuvant hormonal therapy (with [[tamoxifen]] or an [[aromatase inhibitor]]), [[chemotherapy]], and/or [[radiotherapy]]. At present, the tr