Porphyrin

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Porphyrins are a "group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin."[1] Heme is also a component of cytochrome P-450.

Porphyrias are metabolic diseases in the heme biosynthetic pathway characterized by buildup of porphyrin precursors such as porphobilinogen (PBG).

References

  1. ↑ Anonymous (2024), Porphyrin (English). Medical Subject Headings. U.S. National Library of Medicine.
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