Lymphocyte count
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In medicine, the lymphocyte count is "the number of lymphocytes per unit volume of blood."[1] It may further be divided by lymphocyte type, such as B-cell or T-cell, and then T-CD4+ or T-CD8+.
Clinical uses
Measure of nutritional status
A total lymphocyte count less than 2100 is a marker (although a weak marker) of poor nutrition.[2]
Measure of immune status
"A CD4 count of <200 × 10(6) cells/μL is very likely if the ED ALC is <950 × 10(6) cells/μL and less likely if the ALC is >1,700 × 10(6) cells/μL".[3]
In a second study of predicting a CD4+ T-cell of less than 200:[4]
- Total lymphocyte count of more than 2000 has sensitivity or 95%
- Total lymphocyte count of less than 1200 has specificity of 95%
References
- ↑ Anonymous (2024), Lymphocyte count (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Braga M, Gianotti L, Radaelli G, Cristallo M, Baccari P, Dal Cin S et al. (1991 Nov-Dec) Evaluation of the predictive performance of nutritional indicators by receiver-operating characteristic curve analysis. JPEN J Parenter Enteral Nutr 15 (6):619-24. PMID: 1766051
- ↑ Napoli AM, Fischer CM, Pines JM, Soe-lin H, Goyal M, Milzman D (2011). "Absolute lymphocyte count in the emergency department predicts a low CD4 count in admitted HIV-positive patients.". Acad Emerg Med 18 (4): 385-9. DOI:10.1111/j.1553-2712.2011.01031.x. PMID 21496141. Research Blogging.
- ↑ Blatt SP, Lucey CR, Butzin CA, Hendrix CW, Lucey DR (1993). "Total lymphocyte count as a predictor of absolute CD4+ count and CD4+ percentage in HIV-infected persons.". JAMA 269 (5): 622-6. PMID 8093628.