Imipenem: Difference between revisions

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imported>Howard C. Berkowitz
(New page: '''Impipenem''' is a synthetic broad-spectrum antibiotic, which contains a beta-lactam ring structure but is not considered a member of the penicillin or cephalosporin clas...)
 
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'''Impipenem''' is a synthetic broad-spectrum [[antibiotic]], which contains a [[beta-lactam]] ring structure but is not considered a member of the [[penicillin]] or [[cephalosporin]] class. It is a frequent choice for treatment of infections involving multidrug-resistant bacteria, or multiple types of bacteria.
'''Impipenem''' is a synthetic broad-spectrum [[antibiotic]], which contains a [[beta-lactam]] ring structure but is not considered a member of the [[penicillin]] or [[cephalosporin]] class. It is a frequent choice for treatment of infections involving multidrug-resistant bacteria, or multiple types of bacteria.
It is a "semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with [[cilistatin]], a renal dipeptidase inhibitor."<ref>{{MeSH}}</ref>

Revision as of 10:26, 27 June 2010

Impipenem is a synthetic broad-spectrum antibiotic, which contains a beta-lactam ring structure but is not considered a member of the penicillin or cephalosporin class. It is a frequent choice for treatment of infections involving multidrug-resistant bacteria, or multiple types of bacteria.

It is a "semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilistatin, a renal dipeptidase inhibitor."[1]