Natural killer cell/Definition

From Citizendium
Jump to navigation Jump to search

Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T- and B-lymphocytes, they arenot antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory cell surface receptors. T8-lymphocytes share some properties of these cells