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An adenocarcinoma is a highly malignant carcinoma, with a glandular organization. It is a serious diagnosis in neoplasms of solid organs such as the breast and pancreas. It is the most common cancer of lung and colon.

Surgery, usually with adjuvant chemotherapy, offers the only hope of cure. Palliative chemotherapy also is used. The specific antineoplastic agents vary with the affected organ.

Location of tumor Drug
Colon 5-fluorouracil (5FU)
Pancreas 5FU and leucovorin[1]


  1. Jonker D, Bouttell E, Kamra J, Spithoff K, Gastrointestinal Cancer Disease Site Group (21 November 2007), Chemotherapy or radiotherapy for resectable pancreatic adenocarcinoma: clinical practice guidelines, Agency for Healthcare Quality and Research