Molluscum contagiosum

All unapproved Citizendium articles may contain errors of fact, bias, grammar etc. A version of an article is unapproved unless it is marked as citable with a dedicated green template at the top of the page, as in this version of the 'Biology' article. Citable articles are intended to be of reasonably high quality. The participants in the Citizendium project make no representations about the reliability of Citizendium articles or, generally, their suitability for any purpose. This article is currently being developed as part of an Eduzendium student project in the framework of a course entitled Microbiology 201 at Queens College, CUNY. The course homepage can be found at CZ:Biol 201: General Microbiology. For the course duration, the article is closed to outside editing. Of course you can always leave comments on the discussion page. The anticipated date of course completion is May 21, 2009. One month after that date at the latest, this notice shall be removed. Besides, many other Citizendium articles welcome your collaboration!

Molluscum Contagiosum Virus
[[image: Molluscum Contagiosum Virus. |200px|]]
Scientific classification
Kingdom: Virus Family: Poxviridae Genus: Molluscipoxvirus Species: Molluscum contagiosum virus

Introduction

Molluscum Contagiosum Virus was first described and later it was named by Bateman in the early nineteenth century. Over time, there was more cases that were described and similar to this virus, and overtime there was more and more information gathered on this. Goodpasture later described the similarities of molluscum and vaccinia. Molluscum Contagiosum Virus is a poxvirus, which is a member of the family Poxviridae. Poxvirus are viruses that can be a family that infect both vertebrate and invertebrate animals. Molluscum contagiosum is a viral infection that seems to cause lots of papules or nodules on the skin. This disease it thought to infect humans only, but there has been cases where they found animals with Molluscum Contagiosum. This virus is said to be most common in children, but is found in sexually active adults, and those that are not immuned.

Description and Significance

There are various types of Molluscum Contagiosum Virus, and they are most commonly seen on humans, but have been found to be on animals such as chickens, horses, oxes, cows, etc. On humans, they are seen on children and sexually active adults. This virus is very contagious that can spread by contact of infected individuals or by association with fomites. Fomites being infected clothes,

Taxonomy

To explain this further, Molluscum Contagiousum is a poxviruses from the family of Poxviridae. There are four genera, which are Orthopox, Parapox, Yatapox, and Molluscipox. Molluscipox gives rise to the virus Molluxcum Contagiosum. The name for Poxviridae viruses comes from the original grouping of the virus related with the disease that produced poxes on the skin. The subfamily is Chordopoxvirinae, with the Genus Molluscipoxvirus, and the species being MCV. Types of Viruses for each genera: Orthopox: variola virus, vaccinia virus, cowpox virus, monkeypox virus, smallpox ; Parapox: orf virus, pseudocowpox, bovine papular stomatitis virus; Yatapox: tanapox virus, yaba monkey tumor virus; Molluscipox: molluscum contagiosum virus (MCV).

Genome Structure

Genome_MCV

Genome information on various viruses. . By the colaboration of information from experiments conducted by Tatiana G. Senkevicha, Eugene V. Kooninb, Joachim J. Bugertc, a, Gholamreza Daraic and Bernard Mossa, we discovered that the Molluscum Contagiosum Virus is a non-segmented molecule of double-stranded linear DNA with 180,000 to 200,000 nucleotides.It is said that there are 160 genes identified which encode 182 proteins. Among those, 105 proteins are counterparts in OPV (Orthopoxviruses).