Percutaneous transluminal coronary angioplasty

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In medicine, percutaneous transluminal coronary angioplasty (PTCA), also called percutaneous coronary intervention (PCI), is a form of myocardial revascularization in which occurs "dilatation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply."[1]

PTCA may be a treatment for myocardial infarction and an intravascular stent may or may not be left at the site of the stenosis in order to prevent restenosis.[2]

Stenting reduces the rate of restenosis, but should not be done if the patient cannot take clopidogrel, has extensive stenoses, the stenosis is in a very small coronary artery, or if bypass surgery is planned within a few days.[2]

Drug-eluting stents further reduce restenosis compared with bare-metal stents[3], but drug-eluting stents may increase the rate of delayed restenoses. Delayed restenosis may be prevented by taking aspirin combined with clopidogrel.[2]

References

  1. Anonymous (2024), Percutaneous transluminal coronary angioplasty (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. 2.0 2.1 2.2 Keeley EC, Hillis LD (2007). "Primary PCI for myocardial infarction with ST-segment elevation". N. Engl. J. Med. 356 (1): 47-54. DOI:10.1056/NEJMct063503. PMID 17202455. Research Blogging.
  3. Spaulding C, Henry P, Teiger E, et al (September 2006). "Sirolimus-eluting versus uncoated stents in acute myocardial infarction". N. Engl. J. Med. 355 (11): 1093–104. DOI:10.1056/NEJMoa062006. PMID 16971716. Research Blogging.