Vitamin E

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Cambridge Heart Antioxidant Study (CHAOS)[1] -
lack of dose-response gradient
  Nonfatal MI
Vitamin E 800 IU/day 2.0% (11/546)
Vitamin E 400 IU/day 0.6% (3/489)
Placebo 4.2% (41/967)

In biochemistry, vitamin E is a "generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids."[2]

References

  1. ↑ Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ (March 1996). "Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)". Lancet 347 (9004): 781–6. DOI:10.1016/S0140-6736(96)90866-1. PMID 8622332.
  2. ↑ Anonymous, (2009) Vitamin E (English). Medical Subject Headings. U.S. National Library of Medicine.
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