We are creating the world's most trusted encyclopedia and knowledge base.
Once you join us and log in, you'll be able to edit this page instantly!

Vancomycin

From Citizendium, the Citizens' Compendium

Jump to: navigation, search

Image:Statusbar3.png
Main Article
Talk
Definition [?]
Related Articles  [?]
Bibliography  [?]
External Links  [?]
 
This is a draft article, under development. These unapproved articles are subject to a disclaimer.

Contents

Pharmacology

The half life in normal individuals is 4-6 hours.[1]

Adverse effects

Thrombocytopenia

Vancomycin may cause immune thrombocytopenia.[2]

Acute kidney injury

Vancomycin is associated with acute kidney injury if trough levels are above 15 microg/mL.[3] To avoid this, the blood levels of vancomycin should be monitored.[4][5]

References

  1. ↑ DailyMed. vancomycin hydrochloride (Vancomycin Hydrochloride) injection, solution. Retrieved on 2008-01-06.
  2. ↑ Von Drygalski A, Curtis BR, Bougie DW, et al (2007). "Vancomycin-induced immune thrombocytopenia". N. Engl. J. Med. 356 (9): 904–10. DOI:10.1056/NEJMoa065066. PMID 17329697.
  3. ↑ Hidayat LK, Hsu DI, Quist R, Shriner KA, Wong-Beringer A (2006). "High-dose vancomycin therapy for methicillin-resistant Staphylococcus aureus infections: efficacy and toxicity". Arch. Intern. Med. 166 (19): 2138–44. DOI:10.1001/archinte.166.19.2138. PMID 17060545.
  4. ↑ Welty TE, Copa AK (1994). "Impact of vancomycin therapeutic drug monitoring on patient care". Ann Pharmacother 28 (12): 1335–9. PMID 7696720.
  5. ↑ Iwamoto T, Kagawa Y, Kojima M (2003). "Clinical efficacy of therapeutic drug monitoring in patients receiving vancomycin". Biol. Pharm. Bull. 26 (6): 876–9. PMID 12808304.

External links

vancomycin for injection - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).

Retrieved from "http://en.citizendium.org/wiki/Vancomycin"
Views
Personal tools