Systemic lupus erythematosus/Related Articles
From Citizendium, the Citizens' Compendium
- See also changes related to Systemic lupus erythematosus, or pages that link to Systemic lupus erythematosus or to this page or whose text .
- Rheumatology : Medical specialty that deals with the study, diagnosis, and treatment of connective tissue diseases; a subspecialty of internal medicine
- Immunology : The study of all aspects of the immune system in all animals.
- Connective tissue disease : A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides, and thus within the specialty of rheumatology; many involve autoimmunity
Variants and comorbidities
- Central nervous system lupis : Add brief definition or description
- Discoid lupus : Add brief definition or description
- Drug-induced lupus : Add brief definition or description
- Fibromyalgia : Inflammation of the fibrous or connective tissue of the body, characterized by acute and debilitating widespread musculoskeletal pain.
- Lupus nephritis : Add brief definition or description
- Myositis : Add brief definition or description
- Osteonecrosis : Add brief definition or description
- Human leukocyte antigen : Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility complex (MHC) in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.
- Anti-nuclear antibodies : A class of antibodies, members of which are elevated in different autoimmune diseases; the anti-nuclear antibody test is a measurement of the class, complemented by more specific antibody assays
- Anti-nuclear antibody test : A screening test for autoimmune disease, especially systemic lupus erythematosus but also Sjögren's syndrome, scleroderma, etc.; results reported both as a quantitative titer and a qualitative staining pattern observed on immunofluorescence microscopy
- Anti-single-stranded DNA antibodies : Add brief definition or description (ssDNA)
- Anti-double-stranded DNA antibodies : Add brief definition or description (dsDNA)
- Anti-Smith antibodies : Antibodies to a nuclear non-histone protein, highly specific but not sensitive for systemic lupus erythematosus; closely related to anti-ribonucleoprotein antibodies
- C-reactive protein : Globulin that appears in the blood in certain acute inflammatory conditions, such as rheumatic fever, bacterial infections, and neoplastic diseases.
- Erythrocyte sedimentation rate : Add brief definition or description
- Recursive partitioning : A statistical method for multivariable analysis.
- Antimalarial : Rather than all drugs active against malaria, usually a reference to several synthetic analogues of quinine, with applications against malaria and other parasites, but also as disease modifying anti-rheumatic drugs (DMARD) used as immunomodulators in rheumatology
- Non-steroidal anti-inflammatory agent : Medication other than corticosteroids having analgesic, antipyretic and anti-inflammatory activity due to their ability to inhibit the synthesis of prostaglandins.
- Corticosteroid : Steroid hormones mainly produced by the adrenal cortex.
- Danazol : Add brief definition or description
- Dapsone : Add brief definition or description
- Immunoglobulin : Proteins produced by lymphocytes, which are primarily antibodies to attack material the body considers hostile, although some may act as cytokines, signaling to other cells
- Immunosuppressant : Exogenous or endogenous agent, capable of suppressing immune responses of the immune system.
- Azathioprine : An immunosuppressive purine synthesis inhibitor for treating rheumatoid arthritis; formerly a chemotherapy drug.
- Cyclophosphamide : A medication and immunosuppressive agent used to treat lymphoma and leukemia.
- Chlorambucil : Add brief definition or description
- Cyclosporin : Add brief definition or description
- Methotrexate : An inhibitor of tetrahydrofolate dehydrogenase, which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA; it has a wide range of medical applications.
- Hydroxymethylglutaryl-coenzyme A reductase inhibitor : HMG-CoA reductase inhibitors which reduce 3-hydroxy-3-methyl-glutaryl CoA and lower cholesterol synthesis.
- Thalidomide : A biological response modifier with unique properties including anti-inflammatory, immunomodulatory and antiangiogenic effect; also extremely and dramatically teratogenic
- Tumor necrosis factor-alpha : Cytokine involved in systemic inflammation and is a member of a group that stimulates the acute phase reaction
- Antiphospholipid syndrome : presence of antibodies directed against phospholipids (antiphospholipid antibody
- Mixed connective tissue disease : Either an overlap syndrome or distinct disease entity, with overlapping clinical features of scleroderma, systemic lupus erythematosus, polymyositis, and Raynaud's phenomenon
- HIV test : Tests used to detect the presence of the human immunodeficiency virus in serum, saliva, or urine, to detect HIV antibodies, antigens, or RNA.
- Hypersensitivity : In medicine, an altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
- Raynaud's disease : Add brief definition or description
- Raynaud's phenomenon : Add brief definition or description
- Rheumatoid arthritis : A chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints.
- Scleroderma : Add brief definition or description