Oseltamivir

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Oseltamivir structure.jpg
oseltamivir
IUPAC name: see chemistry section
Synonyms: Tamiflu®
Formula: C16H28N2O4

 Uses: influenza A & B

 Properties: sialic acid homolog, neuraminidase inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
312.4045 204255-11-8


Oseltamivir, or oseltamivir phosphate, marketed as Tamiflu®, is an acetamido cyclohexene that is a structural homolog of sialic acid and it is a neuraminidase inhibitor. It is used to treat influenza A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like zanamivir) acts as a transition-state analogue inhibitor of influenza neuraminidase.

Chemistry

Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C16H28N2O4, giving it a molecular mass of 312.4045 g/mol.

External links

The most up-to-date information about Oseltamivir and other drugs can be found at the following sites.