Fludarabine

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(CC) Image: David E. VolkFludarabine monophosphate, an analog of adenosine.
(CC) Image: David E. Volk
Fludarabine monophosphate, an analog of adenosine.

In medicine, fludarabine is a medication that is a antineoplastic agent. It is approved by the U.S. Food and Drug Administration for the palliative treatment chronic lymphocytic leukemia (CLL). It is structurally related to the naturally occuring base adenosine-monophosphate used in both DNA and RNA, but it contains a fluorine atom and the geometry of the ribose ring at position 2' is reversed from that of normal DNA.

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    The most up-to-date information about Fludarabine and other drugs can be found at the following sites.


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