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Eplerenone
From Citizendium, the Citizens' Compendium
Eplerenone, an aldosterone receptor agonist.
Eplerenone is an aldosterone receptor agonist, similar to spironolactone. Because it inhibits the negative regulatory feedback of aldosterone on renin secretion, increased plasma renin, and serum aldosterone, occur with its use. Eplerenone selectively binds to mineralocorticoid receptors relative to its binding to glucocorticoid, progesterone and androgen receptors.
External links
- Eplerenone - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Eplerenone - Drug information for patients from MedMaster (U.S. National Library of Medicine).
- Eplerenone - Detailed information from DrugBank.
