Aldosterone

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(CC) Image: David E. Volk Aldosterone, a mineralcorticoid steroid.
(CC) Image: David E. Volk
Aldosterone, a mineralcorticoid steroid.

Aldosterone, also called (11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al, is a steroid hormone. It is the major mineralcorticoid and it therefore controls electrolyte levels, blood pressure and hydration. Aldosterone is synthesized from corticosterone by oxidation of the C-18 methyl group to form an aldehyde.

Primary aldosteronism underlies about 10% of cases of resistant hypertension.[1]

References

  1. ↑ Douma S, Petidis K, Doumas M, et al (June 2008). Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study. Lancet 371 (9628): 1921–6. DOI:10.1016/S0140-6736(08)60834-X. PMID 18539224.
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