Diabetic ketoacidosis

From Citizendium, the Citizens' Compendium

Jump to: navigation, search


This article is a stub and thus not approved.
Main Article
Talk
Related Articles  [?]
Bibliography  [?]
External Links  [?]
 
http://en.citizendium.org/wiki?title=Diabetic_ketoacidosis&printable=yes
This is a draft article, under development and not meant to be cited but you can help to improve it. These unapproved articles are subject to a disclaimer.

In medicine, diabetic ketoacidosis (DKA) is a type of metabolic acidosis that is a "life-threatening complication of diabetes mellitus, primarily of Type 1 Diabetes Mellitus with severe insulin deficiency and hyperglycemia. It is characterized by excessive lipolysis, oxidation of fatty acids, production of ketone bodies, a sweet smell to the breath (ketosis;) dehydration; and depressed consciousness leading to coma.[1]

Treatment begins with fluid replacement; insulin is not started immediately. It is often secondary to infection or other comorbidity, which must be diagnosed and treated. [2]As it is treated, DKA converts from a high anion gap metabolic acidosis to a normal anion gap metabolic acidosis due to "excretion of ketone anions in the urine"[3], especially if excreted with sodium or potassium cations.

References

  1. ↑ Anonymous, (2009) Diabetic ketoacidosis (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Rucker DW (February 12, 2008), "Diabetic ketoacidosis", eMedicine
  3. ↑ Oh MS, Carroll HJ, Goldstein DA, Fein IA (December 1978). "Hyperchloremic acidosis during the recovery phase of diabetic ketosis". Ann. Intern. Med. 89 (6): 925–7. PMID 102229.
Retrieved from "http://en.citizendium.org/wiki/Diabetic_ketoacidosis"
Views
Personal tools