Acebutolol

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Acebutolol.png
acebutolol
IUPAC name: see chemistry section
Synonyms: dl-acebutolol
Formula: C18H28N2O4

 Uses: hypertention;angina pectoris

 Properties:

 Hazards:

Mass (g/mol): CAS #:
336.4259 37517-30-9


Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interfering with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]

References

General References

The most up-to-date information about Acebutolol and other drugs can be found at the following sites.