Intravenous immunoglobulin
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Cytomegalovirus
Cytomegalovirus in transplant patients may be prevented or treated with intravenous immunoglobulins.
Intravenous immunoglobulins may be used for treatment[1][2]; however, it is not clear that either standard immuneglobulin or hyperimmune globulin are effective.[3] Intravenous immunoglobulins may be combined with antiviral drugs.[4][2]
Intravenous immunoglobulins may be used for prevention in transplantation patients.[5]
References
- ↑ Waid TH, McKeown JW (1995). "Cytomegalovirus hyperimmune globulin for CMV disease refractory to ganciclovir in renal transplantation.". Transplant Proc 27 (5 Suppl 1): 46. PMID 7482820. [e]
- ↑ 2.0 2.1 Emanuel D, Cunningham I, Jules-Elysee K, Brochstein JA, Kernan NA, Laver J et al. (1988). "Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin.". Ann Intern Med 109 (10): 777-82. PMID 2847609. [e]
- ↑ Ljungman P, Cordonnier C, Einsele H, Bender-Götze C, Bosi A, Dekker A et al. (1998). "Use of intravenous immune globulin in addition to antiviral therapy in the treatment of CMV gastrointestinal disease in allogeneic bone marrow transplant patients: a report from the European Group for Blood and Marrow Transplantation (EBMT). Infectious Diseases Working Party of the EBMT.". Bone Marrow Transplant 21 (5): 473-6. DOI:10.1038/sj.bmt.1701113. PMID 9535039. Research Blogging.
- ↑ Alexander BT, Hladnik LM, Augustin KM, Casabar E, McKinnon PS, Reichley RM et al. (2010). "Use of cytomegalovirus intravenous immune globulin for the adjunctive treatment of cytomegalovirus in hematopoietic stem cell transplant recipients.". Pharmacotherapy 30 (6): 554-61. DOI:10.1592/phco.30.6.554. PMID 20500045. Research Blogging.
- ↑ Snydman DR, Werner BG, Heinze-Lacey B, Berardi VP, Tilney NL, Kirkman RL et al. (1987). "Use of cytomegalovirus immune globulin to prevent cytomegalovirus disease in renal-transplant recipients.". N Engl J Med 317 (17): 1049-54. DOI:10.1056/NEJM198710223171703. PMID 2821397. Research Blogging.