CZ:Featured article/Current: Difference between revisions

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(→‎Osteoporosis: Hypertension)
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== '''[[Osteoporosis]]''' ==
== '''[[Hypertension]]''' ==
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----'''Hypertension''' is a multisystem [[disease]] whose hallmark is the elevation of [[blood pressure]].  Primary hypertension has no apparent cause, constitutes the majority of cases, and is treated with measures to reduce blood pressure. Secondary hypertension does have an abnormality that is causing the elevation in blood pressure, such as a [[pheochromocytoma|tumor that secretes hormones]] that raise blood pressure; removing the cause may be curative. Primary hypertension is generally not curable and needs to be managed as a chronic disease.  
As defined by the National Osteoporosis Foundation:
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<font face="Gill Sans MT">Osteoporosis, or porous bone, is a disease characterized by low bone mass and [microarchitectural] structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures, especially of the hip, spine and wrist, although any bone can be affected.</font><ref name=fastfacts>National Osteoporosis Foundation (2005) [https://docs.google.com/viewer?url=http%3A%2F%2Fmedschool.creighton.edu%2Ffileadmin%2Fuser%2Fmedicine%2Fimages%2FCreighton_FIRST%2FOsteo_Spotlight%2FFast_Facts.pdf].</ref>
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The increase in fragility results from both low bone mass and impaired bone quality.
''[[Hypertension|.... (read more)]]''
 
Emphasizing the factor of ‘bone strength’, a factor in addition to and distinct from low bone mass, and the consequent increase risk of sustaining a fracture, a [[National Institutes of Health]] (NIH) Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy has defined osteoporosis in 2001 as
 
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<font face="Gill Sans MT">a skeletal disease characterized by compromised bone strength predisposing a person to an increased risk of fracture. Bone strength primarily reflects the integration of bone density and bone quality...</font><ref name=NIH2001> NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy. (2001)  [http://dx.doi.org/10.1001/jama.285.6.785 Osteoporosis prevention, diagnosis, and therapy]. ''JAMA'' 285(6):785-795. PMID 11176917.</ref>
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Primary osteoporosis can be of two major types: postmenopausal osteoporosis (osteoporosis, postmenopausal) and age-related or senile osteoporosis."
 
Although more common in women, osteoporosis may occur in males.<ref name="pmid18385499">{{cite journal |author=Ebeling PR |title=Clinical practice. Osteoporosis in men |journal=N. Engl. J. Med. |volume=358 |issue=14 |pages=1474–82 |year=2008 |month=April |pmid=18385499 |doi=10.1056/NEJMcp0707217 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=18385499&promo=ONFLNS19 |issn=}}</ref>
 
''[[Osteoporosis|.... (read more)]]''


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! style="text-align: center;" | &nbsp;[[Osteoporosis#References|notes]]
! style="text-align: center;" | &nbsp;[[Hypertension#References|notes]]
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Revision as of 23:45, 5 April 2013

Hypertension


Hypertension is a multisystem disease whose hallmark is the elevation of blood pressure. Primary hypertension has no apparent cause, constitutes the majority of cases, and is treated with measures to reduce blood pressure. Secondary hypertension does have an abnormality that is causing the elevation in blood pressure, such as a tumor that secretes hormones that raise blood pressure; removing the cause may be curative. Primary hypertension is generally not curable and needs to be managed as a chronic disease.

.... (read more)