Anti-Ro: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>Robert Badgett
(Created page with "'''Anti-Ro autobody'''also called '''anti-SS-A''' is associatied with connective tissue disease, such as Sjogren's syndrome and systemic lupus erythematosus, and [[va...")
 
imported>Ro Thorpe
mNo edit summary
Line 1: Line 1:
'''Anti-Ro autobody'''also called '''anti-SS-A''' is associatied with [[connective tissue disease]], such as [[Sjogren's syndrome]] and [[systemic lupus erythematosus]], and [[vasculitis]].
'''Anti-Ro autobody''', also called '''anti-SS-A''', is associatied with [[connective tissue disease]], such as [[Sjogren's syndrome]] and [[systemic lupus erythematosus]], and [[vasculitis]].


Of patients without known illness, 3% will be positive for anti-Ro.<ref name="pmid6600593">{{cite journal| author=Alexander EL, Arnett FC, Provost TT, Stevens MB| title=Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity. | journal=Ann Intern Med | year= 1983 | volume= 98 | issue= 2 | pages= 155-9 | pmid=6600593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6600593  }} </ref>
Of patients without known illness, 3% will be positive for anti-Ro.<ref name="pmid6600593">{{cite journal| author=Alexander EL, Arnett FC, Provost TT, Stevens MB| title=Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity. | journal=Ann Intern Med | year= 1983 | volume= 98 | issue= 2 | pages= 155-9 | pmid=6600593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6600593  }} </ref>

Revision as of 16:58, 25 September 2012

Anti-Ro autobody, also called anti-SS-A, is associatied with connective tissue disease, such as Sjogren's syndrome and systemic lupus erythematosus, and vasculitis.

Of patients without known illness, 3% will be positive for anti-Ro.[1]


Anti-R antibodies may be present three years before development of systemic lupus erythematosus. [1]

Patients with anti-Ro have more systematic illness.[2]

References

  1. 1.0 1.1 Alexander EL, Arnett FC, Provost TT, Stevens MB (1983). "Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity.". Ann Intern Med 98 (2): 155-9. PMID 6600593[e]
  2. Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA et al. (2003). "Development of autoantibodies before the clinical onset of systemic lupus erythematosus.". N Engl J Med 349 (16): 1526-33. DOI:10.1056/NEJMoa021933. PMID 14561795. Research Blogging.