Alcoholism

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Revision as of 15:37, 9 October 2007 by imported>Robert Badgett (New page: ==Treatment== ===Medications=== ===Disulfiram=== A randomized controlled trial showed benefit from disulfiram <ref name="pmid3528541">{{cite journal |author=Fuller RK, Branchey L, ...)
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Treatment

Medications

Disulfiram

A randomized controlled trial showed benefit from disulfiram [1]

Topiramate

A randomized controlled trial of volunteers showed benefit from topiramate.[2]

Naltrexone

Randomized controlled trial showed conflicting benefit from naltrexone with benefit among recent abstainers[3] and no benefit from chronic users[4].


References

  1. Fuller RK, Branchey L, Brightwell DR, et al (1986). "Disulfiram treatment of alcoholism. A Veterans Administration cooperative study". JAMA 256 (11): 1449–55. PMID 3528541[e]
  2. Bankole A. Johnson et al., “Topiramate for Treating Alcohol Dependence: A Randomized Controlled Trial,” JAMA 298, no. 14 (October 10, 2007): 1641-1651, http://jama.ama-assn.org/cgi/content/abstract/298/14/1641 (accessed October 9, 2007).
  3. Anton RF, O'Malley SS, Ciraulo DA, et al (2006). "Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial". JAMA 295 (17): 2003–17. DOI:10.1001/jama.295.17.2003. PMID 16670409. Research Blogging.
  4. Krystal JH, Cramer JA, Krol WF, Kirk GF, Rosenheck RA (2001). "Naltrexone in the treatment of alcohol dependence". N. Engl. J. Med. 345 (24): 1734–9. DOI:10.1056/NEJMoa011127. PMID 11742047. Research Blogging.