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...tite. The two proteins that our project will be mainly involved around are Ghrelin and Leptin as they are extremely important and influential in appetite regu

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...ectives for honours. I also found learning about the actions of leptin and ghrelin very interesting when studying physiology previously in the course.

...into is about the lipostatic interactions and how the two main hormones of Ghrelin and Leptin have a part to play with obesity.

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...m [[adipose tissue]] (fat cells}, and in 2000, another important hormone [[ghrelin]], was identified as a peptide hormone secreted from the [[stomach]]. ...[[ghrelin]] <ref>Dickson S[http://www.neuroendo.org.uk/content/view/26/11/ Ghrelin: A newly discovered hormone ]''Neuroendocrine Briefings''; British Society

...Surg''. 243: 108–114. ''(We examined meal-stimulated responses of insulin, ghrelin, peptide YY (PYY), glucagon-like-peptide-1 (GLP-1), and pancreatic polypept ...cells from direct contact with ingested nutrients, which normally regulate ghrelin levels, and '''this effect may contribute to the efficacy of the procedure

==Ghrelin== *Kojima M ''et al.'' (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. ''Nature'' 402

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On a more experimental level, [[ghrelin]] helps in experimental situations.

Yannielli, P. C. et al. (2007) Ghrelin Effects on the Circadian System of Mice. The Journal of Neuroscience 27(11) ...n young, healthy men is associated with decreased leptin levels, increased ghrelin levels, and increased hunger and appetite.''”)

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...the control of food intake rather than trying to write about npy, leptin, ghrelin and all the other, seemingly endless, gene products that are involved. The "Ghrelin was shown using fluorescent protein tagged NPY neurons, to increase release

...f [[leptin]] (a hormone secreted from fat cells ([[adipose tissue]]) and [[ghrelin]] (a hormone secretd from the stomach when it is empty). Destruction of the ...urons are also regulated by circulating concentrations of [[leptin]] and [[ghrelin]]. They are directly innervated by the NPY/AGRP neurons, which inhibit them

...concentrations sufficient to stimulate hunger and food intake. Preprandial ghrelin surges occur before every meal on various fixed feeding schedules and also ...iological and pathological conditions; and (iv) data on gene variations of ghrelin and its receptor.)