Cefadroxil

(CC) Image: David E. Volk
cefadroxil
IUPAC name: see chemistry section Synonyms: Cefradroxil Formula: C16H17N3O5S
Uses:	antibiotic drug
Properties:	beta-lactam
Hazards:	see drug interactions
Mass (g/mol): CAS #: 363.3883 66592-87-8

Cefadroxil is a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin infections, pharyngitis, and tonsillitis. The compound is active against bacteria due to the beta-lactam moiety and thus is similar to penicillin.

Mechanism of action

Like all beta-lactam antibiotics, cefadroxil binds to specific penicillin-binding proteins located inside the bacterial cell wall, disrupting the last stage of bacterial cell wall synthesis. Due to the defective bacterial cell walls, cell lysis is induced by the autolytic enzymes autolysins. Cefadroxil may interfere with an autolysin inhibitor.

Chemistry

The IUPAC chemical name for cefacroxil is 7-[[2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid and it has chemical formula C₁₆H₁₇N₃O₅S, giving it a molecular mass of 363.3883 g/mol. The compound is active against bacteria due to the presence of the beta-lactam moiety. Like other cephalosporins, it is similar to penicillin but contains a six-membered ring rather than the five-membered ring present in penicillins.

Synonyms and brand names

• Synonyms
• Cefadroxil Monohydrate
• Cefradroxil
• CDX

• Brand names
• Baxan®
• Bidocef®
• Cefa-Drops®
• Cefamox®
• Cephos®
• Duracef®
• Kefroxil®
• Oracefal®
• Sedral®
• Sumacef®
• Ultracef®

External links

The most up-to-date medical information can be found at these sites.

Cefadroxil - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine). Template:MedMaster Template:DrugBank