Protein folding: Difference between revisions
imported>Mitchell McGill No edit summary |
imported>Mitchell McGill No edit summary |
||
| Line 24: | Line 24: | ||
Chaperones make up a unique class of proteins which can aid in the proper folding of other proteins. | Chaperones make up a unique class of proteins which can aid in the proper folding of other proteins. | ||
For more information, see [[Chaperone Proteins]]. | For more information, see [[Chaperone Proteins]]. | ||
== Related Diseases and Disorders == | |||
Alzheimer's. | |||
Prion Disease(s) (Transmissable Spongiform Encephalopathies). | |||
Creutzfeldt-Jakob Disease. | |||
Parkinson's Disease. | |||
Huntington's Disease. | |||
Amyotrophic Lateral Sclerosis. | |||
Revision as of 12:28, 31 December 2008
Proteins are large molecules composed of smaller constituents called amino acids. They are ubiquitous and essential for all life. The 3-dimensional structure and the function of a protein are intimately related. The process by which a protein achieves a final structure is referred to as protein folding.
History of Protein Folding as a Field
C. Anfinsen. K. Dill. Etc.
Proposed Mechanisms
Hydrophobic Collapse. Nucleation-condensation. Viscosity-Collision. Etc.
Thermodynamics
Folding Funnel/Energy Landscapes. Etc.
Chaperones
Chaperones make up a unique class of proteins which can aid in the proper folding of other proteins. For more information, see Chaperone Proteins.
Related Diseases and Disorders
Alzheimer's. Prion Disease(s) (Transmissable Spongiform Encephalopathies). Creutzfeldt-Jakob Disease. Parkinson's Disease. Huntington's Disease. Amyotrophic Lateral Sclerosis.