Curtius rearrangement: Difference between revisions
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imported>Jeanne L. Kuhler (New page: Start your new article here! The '''Curtius rearrangement''' was first reported by Theodor Curtius in 1890. This rearrangement which is sometimes also called the Curtius reaction or Curt...) |
imported>Paul Wormer (rm superfluous sentence) |
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The '''Curtius rearrangement''' was first reported by Theodor Curtius in 1890. This rearrangement which is sometimes also called the Curtius reaction or Curtius degradation proceeds via a highly versatile isocyanate intermediate which can be easily trapped by a variety of nucleophiles, including water, alcohols, and amines via a concerted mechanism which proceeds with retention of configuration. Therefore, this Curtius rearrangement is one of the most widely used organic reactions, with numerous recent examples in the literature. | The '''Curtius rearrangement''' was first reported by Theodor Curtius in 1890. This rearrangement which is sometimes also called the Curtius reaction or Curtius degradation proceeds via a highly versatile isocyanate intermediate which can be easily trapped by a variety of nucleophiles, including water, alcohols, and amines via a concerted mechanism which proceeds with retention of configuration. Therefore, this Curtius rearrangement is one of the most widely used organic reactions, with numerous recent examples in the literature. | ||
Revision as of 01:20, 22 October 2007
The Curtius rearrangement was first reported by Theodor Curtius in 1890. This rearrangement which is sometimes also called the Curtius reaction or Curtius degradation proceeds via a highly versatile isocyanate intermediate which can be easily trapped by a variety of nucleophiles, including water, alcohols, and amines via a concerted mechanism which proceeds with retention of configuration. Therefore, this Curtius rearrangement is one of the most widely used organic reactions, with numerous recent examples in the literature.