Cefoxitin: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
(New page: {{subpages}} {{Chem infobox |align=right |image=center|thumb|250px|{{#ifexist:Template:Cefadroxil.jpg/credit|{{Cefadroxil.jpg/credit}}<br/>|}} |width=250px |molnam...)
 
imported>David E. Volk
mNo edit summary
Line 16: Line 16:
}}
}}


'''Cefoxitin'' is a semi-synthetic, broad-spectrum [[cephalosporin]] type of [[antibiotic]], derived from cephamycin C produced by [[Streptmyces lactamdurans]]. It is administered intravenously.  It is sold under the brand names Mefoxin and Mefoxitin.
'''Cefoxitin''' is a semi-synthetic, broad-spectrum [[cephalosporin]] type of [[antibiotic]], derived from cephamycin C produced by [[Streptmyces lactamdurans]]. It is administered intravenously.  It is sold under the brand names Mefoxin and Mefoxitin.


== Mechanism of Action ==
== Mechanism of Action ==

Revision as of 12:04, 13 July 2009

This article is a stub and thus not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.
(CC) Image: David E. Volk
cefoxitin
IUPAC name: see chemistry section
Synonyms:
Formula: C16H17N3O7S2

 Uses: antibiotic drug

 Properties: beta-lactam

 Hazards: see drug interactions

Mass (g/mol): CAS #:
427.4520 35607-66-0


Cefoxitin is a semi-synthetic, broad-spectrum cephalosporin type of antibiotic, derived from cephamycin C produced by Streptmyces lactamdurans. It is administered intravenously. It is sold under the brand names Mefoxin and Mefoxitin.

Mechanism of Action

Cephalosporin and penicilin-based antbacterial agents inhibit cell wall synthesis of bacteria by binding to penicilin-binding proteins in bacteria through an acylation reaction of the core beta-lactam structure with the cell's proteins.


Chemistry

The IUPAC name for cefoxitin is (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. It has chemical formula C16H17N3O7S2 and molecular mass of 427.4520 grams/mol. Its antibiotic properties are due to its core beta-lactam structure, which is common to all cephalosporins.

References

The most up-to-date information about Cefoxitin and other drugs can be found at the following sites.