S-adenosylmethionine

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In biology and medicine, S-adenosylmethionine is a "physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease."[1]

S-adenosylmethionine's role in treating liver disease is uncertain.[2]

S-adenosylmethionine may help osteoarthritis[3][4]; however, the limited research may be affected by publication bias.

References

  1. ↑ Anonymous (2024), S-adenosylmethionine (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Rambaldi A, Gluud C (2006). "S-adenosyl-L-methionine for alcoholic liver diseases". Cochrane Database Syst Rev (2): CD002235. DOI:10.1002/14651858.CD002235.pub2. PMID 16625556. Research Blogging.
  3. ↑ Hardy ML, Coulter I, Morton SC, et al (August 2003). "S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease". Evid Rep Technol Assess (Summ) (64): 1–3. PMID 12899148. [e] ACP Journal Club review
  4. ↑ Najm WI, Reinsch S, Hoehler F, Tobis JS, Harvey PW (February 2004). "S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495"]. BMC Musculoskelet Disord 5: 6. DOI:10.1186/1471-2474-5-6. PMID 15102339. PMC 387830. Research Blogging.
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