S-adenosylmethionine: Difference between revisions
Jump to navigation
Jump to search
imported>Robert Badgett (New page: In biology and medicine, '''S-adenosylmethionine''' is a "physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It ...) |
imported>Robert Badgett No edit summary |
||
| Line 3: | Line 3: | ||
S-adenosylmethionine's role in treating liver disease is uncertain.<ref name="pmid16625556">{{cite journal |author=Rambaldi A, Gluud C |title=S-adenosyl-L-methionine for alcoholic liver diseases |journal=Cochrane Database Syst Rev |volume= |issue=2 |pages=CD002235 |year=2006 |pmid=16625556 |doi=10.1002/14651858.CD002235.pub2 |url=http://dx.doi.org/10.1002/14651858.CD002235.pub2 |issn=}}</ref> | S-adenosylmethionine's role in treating liver disease is uncertain.<ref name="pmid16625556">{{cite journal |author=Rambaldi A, Gluud C |title=S-adenosyl-L-methionine for alcoholic liver diseases |journal=Cochrane Database Syst Rev |volume= |issue=2 |pages=CD002235 |year=2006 |pmid=16625556 |doi=10.1002/14651858.CD002235.pub2 |url=http://dx.doi.org/10.1002/14651858.CD002235.pub2 |issn=}}</ref> | ||
S-adenosylmethionine may help [[osteoarthritis]]<ref name="pmid12899148">{{cite journal |author=Hardy ML, Coulter I, Morton SC, ''et al'' |title=S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease |journal=Evid Rep Technol Assess (Summ) |volume= |issue=64 |pages=1–3 |year=2003 |month=August |pmid=12899148 |doi= |url= |issn=}} [http://www.acpjc.org/Content/139/1/issue/ACPJC-2003-139-1-020.htm ACP Journal Club review]</ref><ref name="pmid15102339">{{cite journal |author=Najm WI, Reinsch S, Hoehler F, Tobis JS, Harvey PW |title=S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495] |journal=BMC Musculoskelet Disord |volume=5 |issue= |pages=6 |year=2004 |month=February |pmid=15102339 |pmc=387830 |doi=10.1186/1471-2474-5-6 |url=http://www.biomedcentral.com/1471-2474/5/6 |issn=}}</ref>; however, the limited research may be affected by [[publication bias]]. | S-adenosylmethionine may help [[osteoarthritis]]<ref name="pmid12899148">{{cite journal |author=Hardy ML, Coulter I, Morton SC, ''et al'' |title=S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease |journal=Evid Rep Technol Assess (Summ) |volume= |issue=64 |pages=1–3 |year=2003 |month=August |pmid=12899148 |doi= |url= |issn=}} [http://www.acpjc.org/Content/139/1/issue/ACPJC-2003-139-1-020.htm ACP Journal Club review]</ref><ref name="pmid15102339">{{cite journal |author=Najm WI, Reinsch S, Hoehler F, Tobis JS, Harvey PW |title=S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495] |journal=BMC Musculoskelet Disord |volume=5 |issue= |pages=6 |year=2004 |month=February |pmid=15102339 |pmc=387830 |doi=10.1186/1471-2474-5-6 |url=http://www.biomedcentral.com/1471-2474/5/6 |issn=}}</ref><ref name="pmid3318445">{{cite journal |author=Müller-Fassbender H |title=Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis |journal=Am. J. Med. |volume=83 |issue=5A |pages=81–3 |year=1987 |month=November |pmid=3318445 |doi= |url= |issn=}}</ref><ref name="pmid3318444">{{cite journal |author=Vetter G |title=Double-blind comparative clinical trial with S-adenosylmethionine and indomethacin in the treatment of osteoarthritis |journal=Am. J. Med. |volume=83 |issue=5A |pages=78–80 |year=1987 |month=November |pmid=3318444 |doi= |url= |issn=}}</ref><ref name="pmid3318447">{{cite journal |author=König B |title=A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis |journal=Am. J. Med. |volume=83 |issue=5A |pages=89–94 |year=1987 |month=November |pmid=3318447 |doi= |url= |issn=}}</ref>; however, the limited research may be affected by [[publication bias]]. | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 13:37, 10 February 2009
In biology and medicine, S-adenosylmethionine is a "physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease."[1]
S-adenosylmethionine's role in treating liver disease is uncertain.[2]
S-adenosylmethionine may help osteoarthritis[3][4][5][6][7]; however, the limited research may be affected by publication bias.
References
- ↑ Anonymous (2024), S-adenosylmethionine (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Rambaldi A, Gluud C (2006). "S-adenosyl-L-methionine for alcoholic liver diseases". Cochrane Database Syst Rev (2): CD002235. DOI:10.1002/14651858.CD002235.pub2. PMID 16625556. Research Blogging.
- ↑ Hardy ML, Coulter I, Morton SC, et al (August 2003). "S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease". Evid Rep Technol Assess (Summ) (64): 1–3. PMID 12899148. [e] ACP Journal Club review
- ↑ Najm WI, Reinsch S, Hoehler F, Tobis JS, Harvey PW (February 2004). "S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495"]. BMC Musculoskelet Disord 5: 6. DOI:10.1186/1471-2474-5-6. PMID 15102339. PMC 387830. Research Blogging.
- ↑ Müller-Fassbender H (November 1987). "Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis". Am. J. Med. 83 (5A): 81–3. PMID 3318445. [e]
- ↑ Vetter G (November 1987). "Double-blind comparative clinical trial with S-adenosylmethionine and indomethacin in the treatment of osteoarthritis". Am. J. Med. 83 (5A): 78–80. PMID 3318444. [e]
- ↑ König B (November 1987). "A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis". Am. J. Med. 83 (5A): 89–94. PMID 3318447. [e]