Plague: Difference between revisions
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'''Plague''' is a serious infectious disease whose pathogen is ''[[Yersinia pestis]]''. With the exception of the pneumonic and pharyngeal forms, it is spread by the bite of a flea carried by rats. The disease presents in several different. all potentially fatal, ways, all caused by the same organism: | '''Plague''' is a serious infectious disease whose pathogen is ''[[Yersinia pestis]]''. With the exception of the pneumonic and pharyngeal forms, it is spread by the bite of a flea, often ''Xenopsylla cheopis''. The flea [[vector (epidemiology)]] is most often carried by rats, but can also be carried by other animals such as indoor-outdoor [[cat]]s. Plague in cats is not uncommon in some areas, such as the southwest U.S., and is quite treatable; veterinarians in those areas have a high suspicion for it. | ||
The disease presents in several different. all potentially fatal, ways, all caused by the same organism: | |||
#'''bubonic''', with distinctive blue-black skin swellings og [[lymph gland]]s such as in the axilla (i.e., armpit) or groin. The victim also has a high fever, head and body aches, chills, and exhaustion. | #'''bubonic''', with distinctive blue-black skin swellings og [[lymph gland]]s such as in the axilla (i.e., armpit) or groin. The victim also has a high fever, head and body aches, chills, and exhaustion. | ||
#'''meningeal'''. with the symptoms of bubonic plague plus a stiff neck and neurological symptoms | #'''meningeal'''. with the symptoms of bubonic plague plus a stiff neck and neurological symptoms | ||
#'''pharyngeal''', perhaps the mildest form, with sore throat, fever, and swollen lymph nodes in the neck | #'''pharyngeal''', perhaps the mildest form, with sore throat, fever, and swollen lymph nodes in the neck | ||
#'''pneumonic''', the only form transmitted directly between humans. It has abrupt onset with chest pain, cough, difficulty in breathing, high fever, and sputum tinged with blood or pus. It can kill with hours of the onset of symptoms. | #'''pneumonic''', the only form transmitted directly between humans. It has abrupt onset with chest pain, cough, difficulty in breathing, high fever, and sputum tinged with blood or pus. It can kill with hours of the onset of symptoms. It is possible to contract this form from cats as well as humans | ||
#'''septicemic''', rare but also highly lethal, carried in the bloodstream. There are no buboes, although diarrhea will accompany high fever. | #'''septicemic''', rare but also highly lethal, carried in the bloodstream. There are no buboes, although diarrhea will accompany high fever. | ||
[[Streptomycin]], [[doxycycline]], and [[chloramphenicol]] are the usual antibiotics, with streptomycin the drug of choice. Local experience and sensitivity, and preferably laboratory assessments of sensitivity, should guide therapy. | [[Streptomycin]], [[doxycycline]], and [[chloramphenicol]] are the usual antibiotics, with streptomycin the drug of choice. Local experience and sensitivity, and preferably laboratory assessments of sensitivity, should guide therapy. | ||
Revision as of 18:15, 14 February 2009
Plague is a serious infectious disease whose pathogen is Yersinia pestis. With the exception of the pneumonic and pharyngeal forms, it is spread by the bite of a flea, often Xenopsylla cheopis. The flea vector (epidemiology) is most often carried by rats, but can also be carried by other animals such as indoor-outdoor cats. Plague in cats is not uncommon in some areas, such as the southwest U.S., and is quite treatable; veterinarians in those areas have a high suspicion for it.
The disease presents in several different. all potentially fatal, ways, all caused by the same organism:
- bubonic, with distinctive blue-black skin swellings og lymph glands such as in the axilla (i.e., armpit) or groin. The victim also has a high fever, head and body aches, chills, and exhaustion.
- meningeal. with the symptoms of bubonic plague plus a stiff neck and neurological symptoms
- pharyngeal, perhaps the mildest form, with sore throat, fever, and swollen lymph nodes in the neck
- pneumonic, the only form transmitted directly between humans. It has abrupt onset with chest pain, cough, difficulty in breathing, high fever, and sputum tinged with blood or pus. It can kill with hours of the onset of symptoms. It is possible to contract this form from cats as well as humans
- septicemic, rare but also highly lethal, carried in the bloodstream. There are no buboes, although diarrhea will accompany high fever.
Streptomycin, doxycycline, and chloramphenicol are the usual antibiotics, with streptomycin the drug of choice. Local experience and sensitivity, and preferably laboratory assessments of sensitivity, should guide therapy.