Cytochrome P-450 CYP2D6: Difference between revisions
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{{Image|Mmdbimage-36878.png|right|350px|Crystal Structure of Human Cytochrome P450 2d6.}} | |||
In [[biology]], the '''cytochrome P-450 CYP2D6''' is a "[[cytochrome P-450]] enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; [[Adrenergic beta-antagonist|adrenergic receptor antagonist]]s; and [[tricyclic antidepressant]]s. This enzyme is deficient in up to 10 percent of the Caucasian population."<ref>{{MeSH}}</ref> | In [[biology]], the '''cytochrome P-450 CYP2D6''' is a "[[cytochrome P-450]] enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; [[Adrenergic beta-antagonist|adrenergic receptor antagonist]]s; and [[tricyclic antidepressant]]s. This enzyme is deficient in up to 10 percent of the Caucasian population."<ref>{{MeSH}}</ref> | ||
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* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=nuccore Entrez Nucleotide]: [http://www.ncbi.nlm.nih.gov/nuccore/68509919 68509919]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=nuccore_pubmed_weighted&uid=68509919 search] | * [http://www.ncbi.nlm.nih.gov/sites/entrez?db=nuccore Entrez Nucleotide]: [http://www.ncbi.nlm.nih.gov/nuccore/68509919 68509919]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=nuccore_pubmed_weighted&uid=68509919 search] | ||
* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Protein Entrez Protein]: [http://www.ncbi.nlm.nih.gov/protein/40805836 40805836]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=protein_pubmed_weighted&uid=40805836 search] | * [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Protein Entrez Protein]: [http://www.ncbi.nlm.nih.gov/protein/40805836 40805836]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=protein_pubmed_weighted&uid=40805836 search] | ||
* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Structure Entrez Structure]: [http://www.ncbi.nlm.nih.gov/sites/entrez?SUBMIT=y&db=structure&orig_db=structure&term=2F9Q 2F9Q] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 12:49, 29 August 2009
In biology, the cytochrome P-450 CYP2D6 is a "cytochrome P-450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; adrenergic receptor antagonists; and tricyclic antidepressants. This enzyme is deficient in up to 10 percent of the Caucasian population."[1]
External links
- OMIM: 124030
- Entrez Gene: 1565; PubMed: search
- Entrez Nucleotide: 68509919; PubMed search
- Entrez Protein: 40805836; PubMed search
- Entrez Structure: 2F9Q
References
- ↑ Anonymous (2024), Cytochrome P-450 CYP2D6 (English). Medical Subject Headings. U.S. National Library of Medicine.