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...cing the inhibitory effect of ATP. Citrate is an early intermediate in the citric acid cycle, and a high level means that biosynthetic precursors are abundant. ...de and [[water]] by pyruvate decarboxylase and the set of enzymes of the [[citric acid cycle]] (also known as the TCA or Krebs cycle). The products of pyruvate are sequ

...utilise alternative metabolic pathways other than [[glycolysis]] and the [[citric acid cycle]]. A well studied example is sugar metabolism via the keto-deoxy-phosphogl ...[NADH]] obligately fermentative organisms usually do not have a complete [[citric acid cycle]]. Instead of using an [[ATPase]] as in [[respiration]], [[Adenosine triph

...The [[mitochondrion]] (in green) contains the enzymes that catalyze the [[citric acid cycle]] and [[β-oxidation|beta-oxidation]], as well as the [[electron transp

...The [[mitochondrion]] (in green) contains the enzymes that catalyze the [[citric acid cycle]] and [[β-oxidation|beta-oxidation]], as well as the [[electron transp

|discovery of the [[citric acid cycle]]

The second pathway, called the Krebs cycle, or [[citric acid cycle]], occurs inside the mitochondria and is capable of generating enough ATP t

...ut instead rely on amino acids that are eventually [[catabolize]]d by the citric acid cycle during [[aerobic respiration]]. It survives on the remains of less halophi

...gy-storing) ''anabolic'' network as containing the carboxylic acids of the citric acid cycle and employing them to synthesize the biochemical precursors making up the c ...n donors (reducing agents, reductants), sugars, including ribose, from the citric acid cycle intermediate, pyruvate, cell membrane fatty acids from acetate, another int